Fertility and sterility

We describe five patients who developed significant pelvic pain, requiring narcotics, during a controlled ovarian hyperstimulation cycle and who were surgically diagnosed with significant endometriosis. Severe pain, especially if it require…

OBJECTIVE: To evaluate the influence of peroxisome proliferator-activated receptor-gamma (PPAR gamma) ligand (pioglitazone) on tumor necrosis factor-alpha (TNF-alpha)-induced interleukin-8 (IL-8) expression in endometriotic stromal cells (E…

OBJECTIVE: To examine the association between polycystic ovary syndrome (PCOS) and the risk of uterine leiomyomata (UL). DESIGN: Prospective cohort study. SETTING: Participants from the Black Women's Health Study, an ongoing prospective c…

OBJECTIVE: To correlate components of the plasminogen activator (PA) system with fertility outcome parameters in participants in an IVF/intracytoplasmic sperm injection (ICSI) procedure. DESIGN: Case-control study. SETTING: Outpatient cli…

OBJECTIVE: To determine the effects of a thiazolidinedione (TZD) agonist of peroxisome proliferator-activated receptor (PPAR)-gamma, rosiglitazone, in a baboon model of established endometriosis. DESIGN: Prospective, randomized, placebo-co…

A 5-cm umbilical endometriotic lesion associated with a nodule of the posterior aspect of the cervix was discovered in a 32-year-old woman who was consulting for primary infertility. Histological examination of these lesions confirmed smoot…

OBJECTIVE: To analyze prognostic factors that are associated with a discordant outcome in egg recipients sharing oocytes from the same donor. DESIGN: Matched case-control single-center study. SETTING: Private infertility clinic. PATIENT(…

The promoter of P receptor isoform B (PR-B) has recently been shown to be hypermethylated in endometriotic tissues, but one question remains as what causes the aberrant methylation. We show that sustained stimulation of an epithelial-like e…

OBJECTIVE: To evaluate the effects after 10 days of an original treatment combining oral progestins with vaginal raloxifene to maximize the antiproliferative effect on the endometrium. DESIGN: Prospective, randomized, clinical pilot study.…

Started at the grassroot level, increased awareness and investment in research has resulted in unprecedented recognition of endometriosis by the European Parliament, taken up by the Italian Senate in a 5-year action plan. This offers welcom…

OBJECTIVE: To determine the antioxidant, antiinflammatory, and immunomodulatory effects of melatonin on endometrial explants, the distribution of cyclooxygenase-2 (COX-2), the activity of antioxidant enzymes superoxide dismutase (SOD) and c…

OBJECTIVE: To assess whether deep endometriosis has different risk factors compared with endometriosis at other sites. In epidemiological terms, this should be the case if deep endometriosis represents a different condition than ovarian and…

OBJECTIVE: To present a case of successful robotic assisted laparoscopic trachelectomy. DESIGN: Case report. SETTING: Tertiary care facility. PATIENT(S): A 40-year-old female with history of severe endometriosis and adhesions presented w…

OBJECTIVE: To determine the role of interleukin-1 receptor type II (IL-1RII) in the pathogenesis of endometriosis. DESIGN: Cultures of endometrial cells exposed to soluble IL-1RII or the recombinant adenovirus of IL-1RII (rAd-RII). SETTIN…

OBJECTIVE: To assess the value of controlled ovarian hyperstimulation (COH) and IUI in women with unilateral tubal occlusion diagnosed by hysterosalpingography. Hysterosalpingography (HSG) is the most common screening test for tubal patholo…

The aim of this study was to determine the level of soluble HLA-G molecules in the peritoneal fluid of endometriosis patients. The findings demonstrate that a soluble HLA-G level in the peritoneal fluid of women with endometriosis is simila…

OBJECTIVE: To analyze clinicopathologic patterns of early ovarian carcinoma. DESIGN: Retrospective chart and histopathology review. SETTING: Mount Sinai School of Medicine, New York and the Centre Jean Perrin, Clermont Ferrand, France. P…

OBJECTIVE: To report the identification of struma ovarii in a patient with a history of struma ovarii and new hyperthyroidism. DESIGN: Case report. SETTING: Academic research hospital. PATIENT(S): A woman with hyperthyroidism who has str…

OBJECTIVE: To report a case of cystic cervical endometriosis that caused a massive hemorrhage due to rupture of a cyst and successful management with a loop electrosurgical excision procedure (LEEP). DESIGN: Case report. SETTING: Universi…

OBJECTIVE: To evaluate survivin gene expression in granulosa cells from infertile patients and examine the relationship between survivin gene expression and infertile clinical background. DESIGN: Prospective study. SETTING: IVF-ET program…

OBJECTIVE: To determine the accuracy of transvaginal ultrasonography (TVUS) using a modified "tenderness-guided" approach in the diagnosis of deep endometriosis of the cul-de-sac, retrocervical region, and rectovaginal septum. DESIGN: Pros…

OBJECTIVE: To examine the changes of end-tidal carbon dioxide pressure (P(ET)CO(2)) during the menstrual cycle. DESIGN: Controlled clinical study. SETTING: Department of Gynecologic Endocrinology and Reproductive Medicine, Medical Univers…

OBJECTIVE: To investigate the effect of interleukin-6 (IL-6) on ciliary activity within the human fallopian tube in vitro. DESIGN: An experimental laboratory-based study. SETTING: University teaching hospital. PATIENT(S): Fallopian tube …

In elderly women with osteoporosis, raloxifene treatment with vitamin D supplementation improves vaginal maturation index and vaginal pH.

This study aims to determine whether the levonorgestrel-releasing intrauterine system can influence American Society for Reproductive Medicine endometriosis staging scores, as assessed through second-look laparoscopies, and to compare the r…