Fertility and sterility
Fertil Steril
· ISSN (print) 0015-0282
· ISSN (e) 1556-5653
· 3,123 papers in corpus
rct
2007
OBJECTIVE: To evaluate the mechanism of action of recombinant human tumor necrosis factor (TNF)-binding protein-1 by assessing differential expression of messenger RNA (mRNA) for cytokines, matrix metalloproteinases, and growth and adhesion…
lab-animal
2007
OBJECTIVE: Hormonal suppressive therapy is not effective for endometriosis-associated subfertility and can even prevent conception. Medical inhibition of TNFalpha, which has been shown to improve conception, is effective in the prevention a…
lab-animal
2007
OBJECTIVE: To determine the effects of the androgen-like synthetic steroid, danazol, on endothelial cell function and angiogenesis. DESIGN: In vitro cell culture models were designed to investigate three critical steps involved in angiogen…
lab-animal
2007
OBJECTIVE: To investigate the efficacy of imiquimod on endometriosis. DESIGN: Randomized, placebo-controlled, single-blind, experimental study. SETTING: Experimental surgery laboratory at a university in Turkey. ANIMAL(S): Thirty Wistar …
nonrandomized-trial
2007
OBJECTIVE: To describe a safe long-term medical treatment for deeply infiltrating endometriosis, a critical condition characterized by multiple painful symptoms and a high recurrence rate after surgical treatment. DESIGN: Prospective study…
observational
2007
OBJECTIVE: To examine messenger (m) RNA expression of aromatase, cytokines, and adhesion factors in women with and without endometriosis. DESIGN: Patients with endometriosis were compared with control patients. SETTING: University Hospita…
other
2007
case-report
2007
Two patients with spontaneous hemoperitoneum, occurring in the third trimester of pregnancy, had in common previous surgery for moderate endometriosis and successful in vitro fertilization. Although it is not possible to establish a direct …
diagnostic-accuracy
2007
OBJECTIVE: To evaluate the accuracy of endorectal ultrasound examination to ascertain the deepest rectal layer involved in rectal endometriosis. DESIGN: Retrospective study. SETTING: Department of obstetrics and gynecology at a university…
observational
2007
OBJECTIVE: To investigate whether the +1730 G/A polymorphism of the estrogen receptor beta (ER-beta) gene is associated with the risk of endometriosis in a Korean population. DESIGN: Case-control study. SETTING: University Department of O…
lab-animal
2007
OBJECTIVE: To investigate the regulation of estrogen-converting enzymes in human ectopic endometrial tissue. DESIGN: Animal study. SETTING: Academic medical center. ANIMAL(S): Sixty female nude mice with implanted human endometrial tissu…
other
2007
OBJECTIVE: To investigate the expression of cyclooxygenase-2 (Cox-2) and vascular endothelial growth factor (VEGF) in ovarian endometriotic cysts and assess their relation with angiogenesis. DESIGN: Experimental clinical study. SETTING: U…
case-report
2007
OBJECTIVE: To present a case of a unilateral endometrioma with extremely elevated serum CA-125 levels. DESIGN: Case report. SETTING: University hospital. PATIENT(S): A 25-year-old woman with left adnexal mass and extremely elevated serum…
lab-animal
2007
OBJECTIVE: To determine whether immortalized endometriotic cells can be used as potential models to unravel pathophysiology/pathogenesis of endometriosis in humans. DESIGN: In vitro study. Human immortalized endometriotic epithelial and st…
lab-animal
2007
OBJECTIVE: To determine the effects of raloxifene and genistein on experimentally induced endometriosis in a rat model. DESIGN: Prospective, randomized animal study. SETTING: Animal surgery laboratory in a university hospital. ANIMAL(S):…
rct
2007
OBJECTIVE: To investigate the outcomes of intracytoplasmic sperm injection (ICSI) cycles after controlled ovarian hyperstimulation (COH) with GnRH antagonist or GnRH agonist (GnRH-a) in mild-to-moderate endometriosis and endometrioma. DESI…
observational
2007
OBJECTIVE: To investigate the topographical relationship between nerve fibers and peritoneal endometriotic lesions and to determine the origin of endometriosis-associated nerve fibers. DESIGN: Retrospective nonrandomized study. SETTING: U…
rct
2007
This randomized controlled trial compared spontaneous ovulation versus hCG-triggered ovulation in anovulatory women treated with clomiphene citrate. No statistically significant differences were observed between the two groups in terms of o…
observational
2007
The concentration of the soluble form of CD44, a competitive inhibitor for CD44 and hyaluronic acid binding, is higher in the peritoneal fluid of patients with endometriosis than in the peritoneal fluid of patients without endometriosis.
nonrandomized-trial
2007
OBJECTIVE: To evaluate by thorough pathologic analysis the histologic features of the endometrioma wall excised at laparoscopy. DESIGN: Prospective series of consecutive patients. SETTING: Tertiary care, university hospital. PATIENT(S): …
rct
2007
OBJECTIVE: To evaluate the effectiveness for the outcomes of endometriosis-related pain and quality of life of conservative surgery plus placebo compared with conservative surgery plus hormonal suppression treatment or dietary therapy. DES…
other
2007
other
2007
OBJECTIVE: To investigate the expression of heparanase-1, an endoglycosidase that degrades heparan sulfate proteoglycans, in eutopic and ectopic endometrial tissues from women with endometriosis. DESIGN: An immunohistochemical study. SETT…
other
2007
OBJECTIVE: To investigate the localization of the proteins osteopontin (OPN) and L-selectin (SELL). DESIGN: Retrospective nonrandomized immunohistochemical study in a surgically induced rat model of peritoneal endometriosis and in samples …
observational
2007
Endometriosis is characterized by pelvic inflammation that shows an increased number of activated peritoneal macrophages and their secreted products such as cytokines, growth factors, and angiogenic factors. Our results show that activation…