Michał Ciebiera

Background: Endometriosis is a chronic, estrogen-dependent inflammatory disorder. It is associated with hormonal dysregulation, pelvic pain, and a reduced quality of life. Dietary factors may influence disease development and symptom severi…

The development of novel therapies for endometriosis is a rapidly evolving field, encompassing diverse approaches to address this complex and chronic condition. Current treatment modalities, predominantly hormonal therapies and surgical int…

Bartholin glands are paired, mucus-secreting glands, located on both sides of the vaginal opening. Bartholin gland cysts or abscesses mostly occur during the reproductive period and primarily manifest with local pain. The symptomatic ones r…

Endometriosis is a persistent inflammatory condition characterised by chronic pain, increasing the chances of infertility and adverse pregnancy outcomes. However, the existing evidence on this matter lacks consistency. The disease is associ…

Background: Endometriosis is a common gynecological disease linked to significant diagnostic challenges. Cadherin 12 (CDH12), as a member of adhesion molecules, is supposed to be involved in the pathogenesis of this disease and therefore ca…

Introduction: The COVID-19 pandemic has substantially impacted the management of chronic conditions, particularly endometriosis. This study aims to analyze the effects of the pandemic on the quality of life among women with endometriosis un…

Uterine fibroids (UFs) are still mysterious lesions, they are influenced by hormonal imbalances and chronic inflammation, with recent emerging evidence suggesting a role for microbiota. While gastrointestinal and vaginal microbiota in UF pa…

PURPOSE: Endometriosis is a prevalent gynecological condition often requiring invasive procedures for diagnosis. This study aimed to assess mesothelin (MSLN) as a potential non-invasive biomarker by analyzing its levels in peritoneal fluid …

Background: Although significant advancements have been made in the diagnostic and therapeutic methods of gynecological oncology, ovarian cancer continues to pose a significant challenge. The measurement of CA-125 levels is commonly conside…

The most common malignant gynecologic diseases are cervical, uterine, ovarian, vaginal, and vulvar cancer. Among them, ovarian cancer causes more deaths than any other cancer of the female reproductive system. A great number of women suffer…

Mechanisms resulting from the physiological immaturity of the digestive system in children delivered before 32 weeks of gestation and, in particular, different interactions between the microbiome and the body have not been fully elucidated …

This study aimed to evaluate the concentration of osteopontin in peritoneal fluid and plasma as potential biomarkers for diagnosing endometriosis. Osteopontin levels were measured using surface plasmon resonance imaging (SPRI) biosensors in…

Uterine fibromas are an incredibly common condition, affecting the quality of life of both individuals and the whole society and carrying significant direct and indirect costs. UFs are mostly benign tumors, which in many cases can be treate…

PURPOSE: Endometriosis is a common disease with a complex pathomechanism and atypical symptoms, often leading to delayed diagnosis. Currently, the sole method for confirming the presence of the disease is through laparoscopy and histopathol…

Uterine fibroids (UFs) are common tumors in women of reproductive age. It is imperative to comprehend UFs' associated risk factors to facilitate early detection and prevention. Simple relying on surgical/pharmacological treatment of advance…

We would like to announce a new vision of the Journal of Endometriosis and Pelvic Pain Disorders. Thanks to the contribution by former Editors-in-Chief, Associate Editors, and Editorial Board members, as well as all Readers we have a stable…

The development of minimally invasive techniques has led to the creation of innovative alternatives in cases where traditional methods are not applicable. In modern gynecology, hysteroscopy has become the gold standard for the evaluation an…

BackgroundThe main aim of our study involves the analysis of reasons and risk factors for perioperative treatment discontinuation in patients with symptomatic uterine fibroids (UFs) who were qualified for magnetic resonance-guided high-inte…

Oxidative stress (OS) is a condition that occurs as a result of an imbalance between the production of reactive oxygen species (ROS) and the body's ability to detoxify and neutralize them. It can play a role in a variety of reproductive sys…

Previously, the gold standard for the diagnosis of endometriosis involved the performance of laparoscopic surgery, which allows the visualization and histological examination of the endometrial tissue. According to the latest guidelines pub…

For a long time, the uterus had been considered a sterile organ, meaning that under physiological conditions the uterus would not be colonized by bacteria. Based on available data, it may be concluded that the gut and uterine microbiome are…

Uterine fibroids (UFs) are monoclonal, benign tumors that contain abnormal smooth muscle cells and the accumulation of extracellular matrix (ECM). Although benign, UFs are a major source of gynecologic and reproductive dysfunction, ranging …

Objective: The aim of this systematic review is to recap the data obtained from randomized controlled trials looking at new pharmacologic treatments for endometriosis published over the last decade with a focus on non-hormonal therapeutic o…