Chen Y

No ORCID on file · 538 papers in corpus · active 1999-2026

Study types

  • article 121
  • other 45
  • review 26
  • preprint 23
  • meta-analysis 5

Condition tags

  • endometriosis 178
  • adenomyosis 46
  • infertility 45
  • dysmenorrhea 26
  • endometrioma 8
  • chronic_pelvic_pain 6
  • bowel_endometriosis 2
  • bladder_endometriosis 1
  • irritable_bowel_syndrome 1
  • interstitial_cystitis 1
2026
Genes
2026
BMJ open ·doi:10.1136/bmjopen-2025-103421

ObjectivesTo investigate the knowledge, attitudes and practices (KAP) regarding mammary gland hyperplasia (MGH) in adult women from Shandong province, China.DesignA cross-sectional study.SettingThis study was conducted in Shandong province,…

2026
Molecular biomedicine ·doi:10.1186/s43556-026-00472-x

The paradigm shift of lactate from a mere metabolic byproduct to a pleiotropic signaling molecule, coupled with the discovery of lactylation, provides a crucial framework for understanding how metabolic reprogramming drives systemic patholo…

article 2026
Molecular immunology ·doi:10.1016/j.molimm.2026.05.008

BACKGROUND: Endometriosis is a chronic inflammatory disease characterized by immune microenvironment dysregulation, with the IL-33/ST2L signaling axis playing a crucial role in macrophage polarization and disease progression. Despite growin…

2026
Journal of ovarian research ·doi:10.1186/s13048-026-02017-w

Polycystic ovary syndrome (PCOS) is a common reproductive and metabolic disorder with a complex and yet unresolved etiology. Although ovulation induction therapy can improve ovulatory function, the natural pregnancy rate and pregnancy outco…

2026
Communications medicine ·doi:10.1038/s43856-026-01379-y

BackgroundOvarian cancer is a major female reproductive health issue with heterogeneous biological features on its subtypes, which may require different therapeutic strategies. Glucagon-like peptide-1 receptor (GLP-1R) agonists were reporte…

2026
Journal of ovarian research ·doi:10.1186/s13048-026-01973-7

BACKGROUND: This study aims to use non-targeted metabolomics to analyze the metabolic characteristics of follicular fluid in patients with decreased ovarian reserve (DOR) and explore the mediating role of these metabolites in DOR and assist…

other 2026
Journal of pain research ·doi:10.2147/JPR.S557430

BACKGROUND: Endometriosis (EMS) is characterized by pain symptoms that seriously affect patients' quality of life. Gut microbiome-related metabolites (GMRM) play an important role in the process of EMS. However, the role of GMRM in endometr…

article 2026

Wen Shi,1– 3,* Minyi Wang,1– 3,* Zhuang Jin,1– 3 Xiaochuan Chen,1– 3 Jinbo Li,1– 3 Huiling Lai,1– 3 Xiao Li,1– 3 Qiyu Zhong,1– 3 Ye Chen,1– 3 Shuqin Chen1– 3 1Department of Gynecology, The Sixth Affiliated Hospital, Sun Yat-sen Univ…

article 2026

Wen Shi,1–3,* Minyi Wang,1–3,* Zhuang Jin,1–3 Xiaochuan Chen,1–3 Jinbo Li,1–3 Huiling Lai,1–3 Xiao Li,1–3 Qiyu Zhong,1–3 Ye Chen,1–3 Shuqin Chen1–3 1Department of Gynecolog…

other 2026
Journal of pain research ·doi:10.2147/JPR.S608988
review 2026
American journal of physiology. Endocrinology and metabolism ·doi:10.1152/ajpendo.00462.2025

Annexin A2 (ANXA2) is a calcium-dependent protein with high affinity for phospholipids, and its multifunctional nature has drawn increasing attention in the onset and progression of various disorders of the female reproductive system (FRS).…

article 2026
NPJ biofilms and microbiomes ·doi:10.1038/s41522-026-01017-4

Endometriosis (EMS) remains understudied in effective management strategies. The interplay between macrophage dysfunction and microbiota-derived immune signals emerges as a potential mechanism in EMS pathogenesis, suggesting its relevance f…

2026
European journal of medical research ·doi:10.1186/s40001-025-03776-w

BackgroundThis study aimed to analyze the clinical data within one year of the patients who underwent hysteroscopic endometrial polypectomy with levonorgestrel-releasing intrauterine system (LNG-IUS) insertion, and to identify the risk fact…

2026
Journal of ovarian research ·doi:10.1186/s13048-026-02056-3

BACKGROUND: In clinical practice, repeated oocyte retrieval cycles are often necessary for patients with diminished ovarian reserve (DOR). It has been hypothesized that the mechanical stimulation from the initial oocyte pick-up (OPU) proced…

article 2026
Annals of medicine ·doi:10.1080/07853890.2026.2620857

PURPOSE: Adenomyosis (AM) with dysmenorrhea (AMD) is a global public health concern that may involve abnormal brain function and heightened vulnerability to anxiety and depression. This study aimed to investigate static and dynamic regional…

2026
MedComm
2026
Veterinary sciences ·doi:10.3390/vetsci13050438

Fisetin, a flavonoid widely present in natural plants, exhibits diverse pharmacological activities including antioxidant, anti-inflammatory, anti-apoptotic, and anti-aging effects. Its protective roles within the mammalian reproductive syst…

2026
Journal of ovarian research ·doi:10.1186/s13048-026-01995-1

BACKGROUND: The long noncoding RNA (lncRNA) FAM83H-AS1 plays a critical role in the development and progression of various cancers. This study evaluates the feasibility of serum FAM83H-AS1 as a diagnostic and staging marker for ovarian canc…

2026
BMC ophthalmology ·doi:10.1186/s12886-026-04664-5

BACKGROUND: Keratoconus (KC) is a progressive bilateral corneal ectatic disorder characterized by corneal thinning, irregular astigmatism, and subsequent vision impairment. The main purpose of this study is to investigate sex hormone-mediat…

2026
Frontiers in endocrinology ·doi:10.3389/fendo.2026.1747045

BackgroundPolycystic ovary syndrome (PCOS) is associated with an increased risk of type 2 diabetes mellitus (T2DM), and the risk of PCOS increases in patients with T2DM of reproductive age. The bidirectional link between PCOS and T2DM has b…

2026
Frontiers in endocrinology ·doi:10.3389/fendo.2026.1647862

BackgroundCompared with overnight insemination, it remains uncertain whether short-term insemination can improve outcomes in poor responders, and few studies have used cumulative live birth rate as the primary endpoint. The study aims to co…

2026
International journal of women's health ·doi:10.2147/ijwh.s612568

BackgroundPyometra is an uncommon gynecologic disorder characterized by the accumulation of pus within the uterine cavity typically resulting from cervical obstruction. Spontaneous perforation of pyometra (SPP) is extremely rare but may rap…

article 2026
Journal of translational medicine ·doi:10.1186/s12967-025-07648-z

BACKGROUND: Ovarian endometriosis (OEMs) is a primary cause of female infertility and is driven primarily by fibrosis, which disrupts the ovarian follicular microenvironment. Pirfenidone (PFD), an FDA-approved antifibrotic drug, holds promi…

2026
Biomolecules ·doi:10.3390/biom16050719

Regulated cell death is essential for development, tissue homeostasis, host defense, and disease. Beyond apoptosis, it is now clear that other forms of cell death, including ferroptosis, pyroptosis, and necroptosis, also contribute to patho…