Chen Y

Regulated cell death is essential for development, tissue homeostasis, host defense, and disease. Beyond apoptosis, it is now clear that other forms of cell death, including ferroptosis, pyroptosis, and necroptosis, also contribute to patho…

ObjectiveThe ovary, as an important reproductive organ, tightly regulates the litter size of rabbits through its complex network of genes. This study aims to identify candidate genes related to litter size in rabbits through RNA sequencing …

Globally, ovarian cancer remains a leading cause of gynecologic cancer death. This poor prognosis is primarily attributed to advanced disease at diagnosis, a high propensity for recurrence, and the inadequate therapeutic efficacy of current…

Poly(lactic acid-lactic acid) (PLGA) has demonstrated significant application potential in tumor-targeted drug delivery systems due to its excellent biocompatibility, degradability, and multifunctionality for loading various therapeutic age…

Adenomyoma originating from the round ligament of the uterus represents a remarkably uncommon pathological entity. Considering the anatomical course of the round ligament through the inguinal canal, pathological lesions in this structure ma…

BACKGROUND: Adenomyosis is a benign disease characterized by the invasion of endometrial glands and stroma into the uterine myometrium, commonly presenting with abnormal uterine bleeding. METHODS: This paper retrospectively analyzes three …

Endometriosis is a prevalent gynecological condition characterized by the presence of endometrial-like tissue outside the uterus, leading to chronic pelvic pain and infertility. This review aims to shed light on the latest advancements in d…

ObjectiveTo identify the determinants influencing clinical pregnancy outcomes in frozen-thawed embryo transfer (FET) cycles.MethodsA retrospective analysis was conducted on patients who underwent FET at the Department of Reproductive Geneti…

OBJECTIVES: To explore the clinical relevant factors of patients with recurrent and non-recurrent abdominal wall endometriosis after surgical treatment, to further study the relevant risk factors of abdominal wall endometriosis recurrence, …

BackgroundUterine rupture is rare and life-threatening for both mothers and newborns. This study aimed to explore the clinical manifestation, site of rupture, obstetric risk factors, maternal and neonatal complications, and birth outcomes w…

Abdominal wall scar endometriosis (AWE) is a rare endometriosis that usually occurs after gynecological or obstetric surgery and for which surgical resection is the standard treatment. For large tissue defects after resection, abdominal wal…

ObjectiveAlthough struma ovarii (SO) is mostly benign, it is frequently overtreated due to challenges in differentiating it from malignant tumors. Therefore, the purpose of this study was to investigate the clinical, laboratory, ultrasonogr…

ObjectiveWhether large language models (LLMs) can effectively facilitate CM knowledge acquisition remains uncertain. This study aims to assess the adherence of LLMs to Clinical Practice Guidelines (CPGs) in CM.MethodsThis cross-sectional st…

Reproductive endocrine diseases (REDs), including polycystic ovary syndrome, endometriosis, and female infertility, are prevalent reproductive disorders that affect a significant number of women worldwide. Recent research has indicated that…

BackgroundOrganochlorine pesticides (OCPs) are extensively dispersed throughout the environment, which potentially have harmful impacts on the female reproductive system. Therefore, the purpose of this study was to clarify the association b…

BACKGROUND: Endometriosis is a chronic inflammatory disorder affecting reproductive-aged women. The Dietary Inflammatory Index (DII), a measure of diet-related inflammation, has been implicated in various inflammatory diseases, but its role…

Lili Zheng,1,* Huifang Lei,1,* Xiaoyi Tang,2 Yuanyin Zheng,3 Qiuzhen Wu,3 Peixuan Chen,1 Yanhong Chen,1 Liangzhi Cai4,5 1Department of Gynecology, Mindong Hospital Affiliated to Fujian Medical University, Ningde, People’s Republic of China;…

Female infertility is a prevalent condition closely linked with obesity. Current evaluation metrics like body mass index (BMI) and waist circumference (WC) have limitations. Relative fat mass (RFM) is a newer, more accurate obesity metric, …

BackgroundSpontaneous abortion has been associated with higher risk of type 2 diabetes mellitus (T2DM) and gestational diabetes mellitus (GDM), while the evidence remains equivocal. This study aimed to examine the association between sponta…

BACKGROUND: Endometriosis (EM) is a common hormone-dependent and chronic inflammatory disease affecting women of reproductive age, characterized by pelvic pain, infertility, and reduced quality of life. Laparoscopic surgery is a primary tre…

BACKGROUND: Endometriosis is a common disease for women of reproductive ages. Individuals with accelerated biological aging are at a higher risk of developing various diseases, however, the effect of biological aging on the risk of endometr…

BackgroundPrevious studies have focused on the effects of ambient air pollutant levels on assisted reproduction. This research focused on the combined effects of lower concentrations of air pollutants and multiple environmental factors on m…

BackgroundCervical intraepithelial neoplasia grade 2 (CIN2) is one of the precursor stages before cervical lesions develop into cervical cancer. The spontaneous development of CIN2 is ambiguous. One part of CIN2 lesions will progress to cer…

BACKGROUND: Uterine fibroids and endometriosis are common benign gynecological diseases affecting the health of women of childbearing age, characterized by high incidence and recurrence rates. Despite the increasing global emphasis on women…

Endometriosis is a prevalent reproductive disorder that affects a significant number of women globally. Cathepsins, which are lysosomal cysteine proteases, contribute to several physiological and pathological processes, including the attach…