Hirotaka Ota

BACKGROUND: One immune characteristic of endometriosis is a decrease in natural killer (NK) cell activity. This study was performed to determine whether an abnormal immune reaction in an endometriosis animal model could be transferred to an…

This study was undertaken to determine the expression of endothelial nitric oxide synthase (NOS) mRNA in ectopic endometrium in adenomyosis. Endothelial NOS mRNA expression was investigated by in situ hybridization using a human endothelial…

ObjectiveTo investigate the expression of xanthine oxidase in eutopic and ectopic endometrium in endometriosis and adenomyosis.DesignImmunohistochemical identification of xanthine oxidase in endometrial tissues by using polyclonal antibody.…

ObjectiveTo determine the expression of glutathione peroxidase (GPx) in the eutopic and ectopic endometria during the menstrual cycle in endometriosis and adenomyosis.DesignImmunohistochemical identification of GPx in endometrial tissues id…

Recent studies have shown that synthase for nitric oxide or scavenger enzymes is distributed throughout the endometrium. We have reported that endothelial nitric oxide synthase, originally identified in vascular endothelial cells, is distri…

ObjectiveTo determine the expression of superoxide dismutase (SOD) in the endometrium during the menstrual cycle in endometriosis and adenomyosis.DesignImmunohistochemical identification of SOD in endometrial tissues using the monoclonal an…

ObjectiveTo determine the expression of endothelial nitric oxide synthase in the endometrium during the menstrual cycle in endometriosis and adenomyosis.DesignImmunohistochemical identification of endothelial nitric oxide in endometrial tis…

ObjectiveTo evaluate the pathophysiologic role of heat shock proteins and to examine the effect of danazol on these proteins in patients with endometriosis and adenomyosis.DesignImmunohistochemical identification of human heat shock protein…

OBJECTIVE: To assess the role of beta 1-integrin and E-cadherin molecules in the eutopic glandular epithelium in patients with endometriosis or adenomyosis. STUDY DESIGN: Twenty-four patients with endometriosis, and 22 patients with adenomy…

ObjectiveTo assess the effects of danazol on immunocompetent cells, human leukocyte antigen (HLA) expression, and adhesion molecules in the eutopic endometrium of patients with endometriosis.DesignAntigens were localized immunohistochemical…

PROBLEM: Are T cell subsets including gamma delta T cells. HLA antigens or adhesion molecules, expressed in eutopic and ectopic endometria in patients with endometriosis and adenomyosis? METHODS: Subjects consisted of 23 patients with adeno…