Yu C

OBJECTIVE: To investigate the association between delivery/abortion methods, allergy history, and endometriosis (EM) risk. METHODOLOGY: This prospective case-control study was conducted at the First Affiliated Hospital of Naval Medical Uni…

BACKGROUND: Ovarian endometriosis (OE) is a leading cause of female infertility. Our previous work identified iron overload-driven oxidative stress and mitochondrial dysfunction in granulosa cells as key pathogenic features, yet the mechani…

N6-methyladenosine (m6A) is a critical regulator of female reproductive physiology, yet existing reviews have focused predominantly on oocytes. The objective of this review is to systematically evaluate the regulatory effects of m6A through…

Polycystic ovary syndrome is the primary cause of female infertility. Growing evidence suggests that dysregulation of amino acid metabolism plays a significant role in the onset and progression. However, the underlying mechanism remains unc…

ObjectiveTo investigate the efficacy of the Er Zhi Tian Gui Formula (EZTGF) in diminished ovarian reserve (DOR) patients undergoing in vitro fertilization-embryo transfer (IVF-ET); to examine the pharmacological mechanism of EZTGF in inhibi…

ObjectiveTo investigate the effects of cold environment exposure on female reproductive capacity and explore its potential regulatory mechanisms.MethodsFemale mice were subjected to cold water immersion to simulate cold environment exposure…

Protein O-GlcNAcylation is a post-translational modification coupled to cellular metabolic plasticity. Aberrant O-GlcNAcylation has been observed in many cancers including endometrial cancer (EC), a common malignancy in women. However, clin…

AbstractResearch on social disparities in pain and pain treatment has grown substantially in recent decades, as reflected in a growing number of review articles on these topics. This scoping review of reviews provides a macrolevel overview …

BackgroundInfertility is a public health issue closely related to obesity. However, the relationship between obesity-related indicators and infertility is currently uncertain. The present study aimed to explore the association between obesi…

ObjectiveThe objective of this study was to investigate the correlation between various factors and the clinical outcomes of Intrauterine Insemination (IUI) in both young and aged patients, aiming to provide a theoretical basis for clinical…

INTRODUCTION: Endometriosis (EM) is a chronic estrogen-dependent condition characterized by the growth of endometrial-like tissue outside the uterus, posing a significant burden on reproductive-aged women. Previous research has shown a corr…

Yangshuo Li,1,* Zhihao Zhou,1,2,* Xiaolan Liang,1,* Jie Ding,1 Yalun He,1 Shuai Sun,1 Wen Cheng,1 Zhexin Ni,1,3 Chaoqin Yu1 1Department of Traditional Chinese Gynecology, the First Affiliated Hospital of Naval Military Medical University (C…

BackgroundAn imbalance of the pro-oxidant and antioxidant profiles in the body contributes to the development of diseases, including female infertility.MethodsIn this study, we performed a secondary analysis of the National Health and Nutri…

BACKGROUND: Semaphorin 3A (Sema3A) is a member of neural guidance factor family well-known for inducing the collapse of nerve cell growth cone and regulating nerve redistribution. It also has been characterized as an immunoregulatory and tu…

ObjectiveThis research aimed to assess the effectiveness of manual therapy in alleviating pain among women undergoing primary dysmenorrhea (PD).MethodsAll randomized controlled trials (RCTs) regarding manual therapy for PD were searched fro…

Endometriosis (EMS) is a chronic inflammatory disease frequently associated with infertility. N6-methyladenosine (m6A) methylation, the most common form of methylation in eukaryotic mRNAs, has gained attention in the study of female reprodu…

Endometriosis (EMs) is a common chronic inflammatory disease which is characterized by multiple clinical symptoms and high recurrence rate due to the absence of effective therapies. Huayu Jiedu Formula (HYJDF), is a traditional Chinese medi…

Puerarin has been reported to have anti-inflammatory, antioxidant, immunity enhancement, neuroprotective, cardioprotective, antitumor, and antimicrobial effects. However, due to its poor pharmacokinetic profile (low oral bioavailability, ra…

ObjectivesTo analyze the correlation between age and sperm DNA fragmentation index (DFI), and determine whether the number of eggs retrieved from the female partner was associated with the impact of sperm DFI on clinical pregnancy rates.Met…

BACKGROUND: Endometriosis (EMs) is a common chronic inflammatory disease which is characterized by multiple clinical symptoms and high recurrence rate due to the absence of effective therapies. Huayu Jiedu Formula (HYJDF), is a traditional …

BackgroundThe effects of acupuncture on female infertility remain controversial. Also, the variation in the participant, interventions, outcomes studied, and trial design may relate to the efficacy of adjuvant acupuncture. The aim of the st…

OBJECTIVE: The aim of this study was to investigate whether curcumin has a therapeutic effect on endometriosis (EM) and to determine the specific mechanism. METHODS: Network pharmacology was used to obtain the core targets of curcumin for …