Integrative single-cell analysis reveals Bu-Shen-Huo-Xue Formula rescues iron-overloaded ovarian function via rewiring IFN-γ/JAK/STAT/CXCL10-driven immune-stromal interactions and BNIP3-mediated mitophagy in endometriosis

Zhexin Ni, Qianqian Zhao, Yangshuo Li, Shanshan Mei, Jin Yu, Jie Ding, X Liang, Shuai Sun, Yuqing Wang, Wen Cheng, Wei Zhou, Chaoqin Yu
In: Phytomedicine · 2026 · vol. 157 , pp. 158343 · doi:10.1016/j.phymed.2026.158343 · PMID:42208103 · W7162195101
article OA: closed CC0
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study integrated single-cell data to show Bu-Shen-Huo-Xue Formula reverses iron overload in ovaries by altering immune-stromal crosstalk and promoting mitophagy, impacting endometriosis progression.

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endometriosis

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