Frontiers in veterinary science

A 10-year-old Labrador Retriever bitch, spayed at 2 years of age, was presented to our veterinary care facility with a history of vulvar swelling, vaginal discharge, and male attraction for over 1 month. Vaginoscopy revealed edema and redde…

Pelvic inflammatory disease (PID) is a complex multifactorial infectious disorder of the female reproductive tract, associated with severe long-term sequelae including infertility, ectopic pregnancy, and chronic pelvic pain, as well as elev…

Phenolic compounds from olive mill wastewater (OMWW) have a strong antioxidant capacity, so there is increasing interest in using them in feed for livestock, including pigs. This study tested the effects of dietary supplementation with a po…

BackgroundFollicular fluid extracellular vesicles (EVs) have emerged as critical mediators of intercellular communication during oocyte development. This study investigates the role of small non-coding RNAs (SncRNAs) within porcine follicul…

IntroductionPituitary pars intermedia dysfunction (PPID) is an age-related endocrinopathy associated with elevated systemic inflammation, and specifically an upregulation of interleukin-8 (IL-8). It is unknown if PPID in concomitant with re…

The hypothalamus plays a vital role in reproductive processes. Previous studies have identified hypothalamic miRNAs involved in mammalian reproduction, but the miRNA profiles induced by photoperiod changes remain unclear. In this study, we …

IntroductionPersistent breeding-induced endometritis (PBIE) remains a major problem in equine reproduction. This disorder is characterized by prolonged post-breeding inflammation and is associated with advanced age, reduced endometrial qual…

Adding plant extracts to diets to enhance sow performance and health is widely regarded as a healthy and sustainable practice. In promoting antibiotic-free farming, plant extracts have emerged as a leading solution for enhancing sow fertili…

Organoids have already shown great promise as research tools in human medicine. However, in veterinary medicine, such applications are limited and largely confined to canine organoids. In the Cross Health context, the potential of canine or…

Uterine torsion is a rare condition in dogs, typically associated with pregnancy or uterine pathology. A 5-year-old, female intact, Siberian-Husky presented with a history of lethargy and constipation for 3 days. Physical examination reveal…

Gonadal dysfunction resulting from conditions such as premature ovarian insufficiency, chemotherapy-induced damage, or genetic disorders often leads to infertility and hormone imbalance. Although assisted reproductive technologies and hormo…

The purpose of this review is to evaluate the effectiveness of large animal models in gynecology research and provide future perspectives. Gynecological diseases are diverse and pose a serious threat to women's physical and mental health. I…

IntroductionEmerging evidence indicates that dysregulated palmitic acid (PA) homeostasis plays a key role in inducing lipotoxicity and cellular dysfunction in mammalian endometrial epithelial cells. While this phenomenon has been documented…

Research on circular RNA (circRNA) in poultry increasingly explores its role as a potential regulator in various diseases. It has also shown differential expression of circRNAs in infected tissues, signifying their participation in disease …

Gynecological diseases pose substantial risks to female reproductive health and overall wellbeing. To improve disease prevention and treatment, researchers continue to develop experimental models that faithfully replicate key features of th…

IntroductionThe glutaraldehyde test (GAT) allows for animal-side semi-quantitative estimation of fibrinogen and gamma-globulin concentrations in blood samples of adult cattle and therefore detection of inflammatory disease conditions. Howev…

The giant anteater (Myrmecophaga tridactyla) is a vulnerable species in South America and is considered endangered or near extinction in Central America. Therefore, studies describing the reproductive characteristics of this species are piv…

IntroductionNucleotide-binding domain (NOD)-like receptors (NLRs) are expressed in the endometrium, and involved in modulating the female innate immune responses. There are conceptus-endometrial interactions during pregnancy, which ensure i…

The broad conceptualization of fertility preservation and restoration has become already a major concern in the modern western world since a large number of individuals often face it in the everyday life. Driven by different health conditio…

A 9-month-old, female Pomeranian dog presented with vomiting and lethargy. Ultrasonography revealed multilobulated anechoic round shape structures at the ovarian and uterine locations. Through computed tomography scan, an extensive non-cont…

A 30-year-old Lusitano stallion presented with an enlarged right epididymis. The ultrasound scan revealed a cyst-like formation and the histopathological examination was compatible with epididymal cyst located at the body/tail transition, e…

Vitamin D plays a role in anti-inflammatory processes, and the alteration of its metabolism is associated with the inflammatory processes of pancreatitis. This study was performed to evaluate the expression of the vitamin D receptor (VDR) a…

IntroductionContraception is often required for management and population control purposes in group-housed and free-roaming non-human primates. Long-acting reversible contraceptives, including subdermal progestin-releasing implants, are pre…

The modulation of inflammation is pivotal for uterine homeostasis. Here we evaluated the effect of the oestrus cycle on the expression of pro-inflammatory and anti-inflammatory markers in a cellular model of induced fibrosis. Mare endometri…

The canine corpus luteum (CL) is able to synthetise, activate and deactivate 17b-estradiol (E2) and also expresses nuclear estrogen receptors in a time-dependent manner during diestrus. Nevertheless, we are still missing a better comprehens…