René Wenzl
ORCID: 0000-0001-6177-1421
· 74 papers in corpus
article
2015
Trotz der hohen klinischen Relevanz der Endometriose war es bisher nicht möglich eine Spezialisierung im Rahmen eines zertifizierten Weiterbildungsprogrammes anzustreben/anzubieten.
article
2014
ObjectiveIn addition to dysmenorrhea, dyspareunia, and subfertility, pain in the lower extremities has been described to be a further complaint in women affected by endometriosis, and lysis of nerve entrapment was thought to be associated w…
article
2013
Endometriosis compromises the quality of life of countless women worldwide and is a leading cause of disability. Clinical symptoms of endometriosis can be very heterogeneous leading to a long interval between onset of symptoms and surgical …
article
2011
BACKGROUND Enhanced proliferation and survival of eutopic endometrial cells from patients with endometriosis compared with healthy women is associated with abnormal activation of extra-cellular signal-regulated kinases 1 and 2 (ERK1/2). Giv…
article
2011
ObjectiveTo establish the prevalence of endometriosis metastatic to pelvic sentinel lymph nodes (PSLN) in women with ovarian and/or peritoneal endometriosis.DesignProspective clinical study.SettingAcademic research institution.Patient(s)Wom…
article
2010
Family incidence of endometriosis in first-, second-, and third-degree relatives: case-control study
BACKGROUND: Initial publications examining the hereditary aspects of endometriosis appeared in the early seventies and demonstrated an up to seven-fold risk for endometriosis in first-degree relatives of endometriosis patients. The aim was …
rct
2009
BACKGROUND: Implanon has been reported to be effective in the treatment of dysmenorrhea. We compared the therapeutic efficacies of depot medroxyprogesterone acetate (DMPA) and Implanon with regard to pain relief in women with endometriosis.…
article
2007
In der medikamentösen Therapie der endometriose-assoziierten Schmerzsymptomatik kommen neben GnRH-Analoga und Danazol® seit vielen Jahren Gestagene zum Einsatz. Ein akzeptiertes „Standard-Langzeittherapeutikum“ stellt dabei Depot-Medroxypro…
article
2005
Fragestellung: Unter Endometriose wird das Vorkommen von Endometrium außerhalb der Gebärmutterhöhle verstanden, wobei eine Endometriosis interna uteri (Adenomyosis uteri) von einer Endometriosis externa uteri unterschieden wird. Warum es zu…
article
2005
Hintergrund: Endometriose ist eine Erkrankung die verschiedenste Erscheinungsformen zeigen kann und für die Diagnostik eine schwierig fassbare Entität darstellt. Aus epidemiologischer Sicht gibt es eine Reihe von Parametern, die häufig mit …
article
2005
ObjectiveTo evaluate the local matrix metalloproteinase 1 (MMP-1), estrogen receptor (ER) alpha, and ERbeta protein expression in eutopic and dystopic tissue from patients with endometriosis and to compare the endometrial expression pattern…
article
2005
Fragestellung: Die Endometriose stellt neben Malignomen des weiblichen Genitale die häufigste Ursache für organdestruktives Wachstum im kleinen Becken dar, wodurch sich klassische Symptome wie Dypareunie, Dysmenorrhoe, Dysdefäkation oder Dy…
article
2005
Fragestellung: Die Endometriose stellt neben Malignomen des weiblichen Genitale die häufigste Ursache für organdestruktives Wachstum im kleinen Becken dar, wodurch sich klassische Symptome wie Dypareunie, Dysmenorrhoe, Dysdefäkation oder Dy…
article
2004
article
2003
Interleukin (IL)-6 has been implicated in the etiology of endometriosis. A single nucleotide polymorphism (SNP) at position -174 in the IL-6 gene promoter appears to influence IL-6 transcription rates in vitro and basal IL-6 levels in vivo.…
review
2003
Endometriosis is a multifactorial disease affecting up to 15% of women of reproductive age. This condition is characterized by the presence and growth of endometrial cells outside the uterus. Susceptibility to endometriosis depends on compl…
article
2002
PurposeCatechol-O-methyltransferase (COMT) inactivates the estradiol metabolites, 2-hydroxy and 4-hydroxy catechols, which have been implicated in the pathogenesis of endometriosis. A COMT valine to methionine polymorphism (G-to-A) in exon …
article
2002
ObjectiveTo investigate the association between the 306-base pair insertion polymorphism in intron G of the progesterone receptor (PROGINS) and endometriosis.DesignCase-control study.SettingTertiary care center.Patient(s)Ninety-five white w…
article
2002
article
2002
article
2001
ObjectiveTo investigate microvessel density in adenomyosis compared to the endometrium in patients with adenomyosis and in normal controls.DesignUterine paraffin-embedded histologic specimens were immunostained for CD34. The area with the h…
article
1999
Surgical treatment of endometriosis should be done during laparoscopy, which is obligatory for the diagnosis of the disease. In case of continuing postoperative symptoms, a medical treatment should be administered. As endometriosis is a hor…
article
1999
Endometriosis is one of the most common benign gynecological diseases, affecting an estimated 10-15% of all premenopausal women. In this open multicentric prospective study, we investigated the effectiveness and tolerance of a gonadotropin …
article
1998
We performed an immunohistochemical study on paraffin-embedded tissues to evaluate the invasion pattern of endometriotic implants by determination of matrix metalloproteinase (gelatinase A) expression. Endometriotic tissues (n=32) and uteri…