Bianca De Leo

No ORCID on file · 15 papers in corpus · active 2012-2025

Study types

  • article 9
  • other 3
  • dissertation 1
  • preprint 1
  • review 1

Condition tags

  • endometriosis 15
  • mesh:D004715 6
  • mesh:D017699 2
  • interstitial_cystitis 2
  • dyspareunia 1
  • chronic_pelvic_pain 1
  • mesh:D004414 1
  • infertility 1
other 2025
Reproduction & fertility ·doi:10.1530/RAF-23-0083

ABSTRACT: Dyspareunia, or pain during sex, is a common and often debilitating symptom in individuals with endometriosis and/or interstitial cystitis/bladder pain syndrome (IC/BPS). Despite its significant impact on quality of life, it is fr…

other 2023
International journal of molecular sciences ·doi:10.3390/ijms24032422

Chronic pain induced by endometriosis is a maladaptive pain experienced by half of women with this disease. The lack of pharmacological treatments suitable for the long-term relief of endometriosis-associated pain, without an impact on fert…

article 2023
·doi:10.5281/zenodo.7645990

Chronic pain induced by endometriosis is a maladaptive pain experienced by half of women with this disease. The lack of pharmacological treatments suitable for the long-term relief of endometriosis-associated pain, without an impact on fert…

article 2022
·doi:10.5281/zenodo.6985181

The aim of this study was to develop and refine a heterologous mouse model of endometriosis-associated pain in which non-evoked responses, more relevant to the patient experience, were evaluated. Immunodeficient female mice (N = 24) were ea…

article 2022
Biomedicines ·doi:10.3390/biomedicines10020501

The aim of this study was to develop and refine a heterologous mouse model of endometriosis-associated pain in which non-evoked responses, more relevant to the patient experience, were evaluated. Immunodeficient female mice (N = 24) were ea…

article 2021
Science translational medicine ·doi:10.1126/scitranslmed.abd6469

< 0.05) in a mouse model of peritoneal inflammation as well as in a mouse model of endometriosis. We conclude that the NPSR1/NPS system is a genetically validated, nonhormonal target for the treatment of endometriosis with likely increased …

article 2021
Reproduction & fertility ·doi:10.1530/raf-20-0072

Endometriosis is a chronic neuroinflammatory pain condition affecting ~180 million women worldwide. Surgical removal or hormonal suppression of endometriosis lesions only relieves pain symptoms in some women and symptomatic relapse followin…

review 2021
Pain ·doi:10.1097/j.pain.0000000000002248

ABSTRACT: Endometriosis (ENDO) and interstitial cystitis/bladder pain syndrome (IC/BPS) are chronic pain conditions for which better treatments are urgently needed. Development of new therapies with proven clinical benefit has been slow. We…

other 2020
Scientific reports ·doi:10.1038/s41598-020-58362-3

Endometriosis is a common gynaecological disease of women in reproductive age, and is thought to arise from retrograde menstruation and implantation of endometrial tissue, mostly into the peritoneal cavity. The condition is characterized by…

article 2020
Scientific reports ·doi:10.1038/s41598-020-62492-z

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

article 2020
preprint 2020
·doi:10.1101/2020.07.31.209106

Abstract Objective To characterise peritoneal macrophage populations in women with suspected endometriosis and assess if they are correlated with severity of pelvic pain symptoms. Design Flow cytometry analysis of peritoneal fluid samples a…

article 2019
dissertation 2017

During the normal menstrual cycle, the human endometrium undergoes extensive tissue remodelling under the influence of ovarian-derived hormones. The endometrium has well defined stromal and epithelial compartments with the former containing…

article 2012
·doi:10.5301/je.2012.9232

Purpose To investigate expression of molecular transporters and CYP4B1 in endometrium from women with and without endometriosis. Methods Expression of genes encoding proteins: ATP-binding cassette sub-family G member 1 (ABCG1), aquaporin 3 …