Reproduction & fertility

AbstractThis study aimed to investigate whether an early LH surge during controlled ovarian stimulation (COS) affects pregnancy outcomes in patients with polycystic ovary syndrome (PCOS) undergoing assisted reproductive technology (ART) and…

ABSTRACT: Endometriosis is a common, inflammatory condition impacting 200 million women and those assigned female at birth, where 25-40% experience infertility. Ovarian endometriosis is known to decrease anti-Müllerian hormone (AMH) levels …

Adenomyosis and endometriosis are two sister diseases that cause menstrual pain and other symptoms. We have previously reported that patients with these conditions have a less active 'calm-and-rest' system and a more active 'stress-and-aler…

ABSTRACT: Decidualization of human endometrial stromal cells (ESCs) precedes the successful implantation of a human embryo. Improper decidualization has been reported in numerous conditions associated with infertility, including endometrios…

AbstractChronic endometritis (CE) is a localized inflammatory disorder of the endometrium characterized by plasma cell infiltration, most often identified by CD138 immunostaining. Its diagnosis remains problematic due to the absence of stan…

Graphical abstractAbstractInfertile patients initially undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) with fresh embryo transfer often lack baseline indications for preimplantation genetic testing for aneuploi…

AbstractLow oocyte retrieval (LOR), defined as oocytes retrieved from <50% of mature follicles, significantly impacts IVF success, especially in patients with diminished ovarian reserve (DOR). Predictive models tailored for this population …

Graphical abstractAbstractThe endometrium is the primary site of embryo implantation. Cellular senescence within the endometrium can be broadly categorised into normal cyclical senescence and pathological excessive senescence. Normal cyclic…

ABSTRACT: Endometriosis, with a global prevalence of approximately 18%, is a chronic condition that significantly impacts patients' quality of life and increases the risk of depression. Despite growing public health concerns, access to heal…

Endometriosis is a chronic pain condition that affects >190 million people worldwide. It is recommended in clinical guidelines to remove the most common type of endometriosis, 'superficial peritoneal endometriosis' (SPE), if it is diagnosed…

AbstractOncofertility has emerged as a critical interdisciplinary field addressing the reproductive challenges faced by cancer patients, particularly those undergoing chemotherapy. While chemotherapeutic agents remain indispensable in cance…

AbstractHydrosalpinx is a chronic pathological manifestation seen in approximately 30% of tubal disease cases. In addition to contributing to infertility and pelvic pain, hydrosalpinx has been associated with early pregnancy loss and reduce…

Graphical abstractAbstractThis study aimed to characterize phase-specific dynamics of androstenedione and estradiol across IVF/ICSI treatment, identify predictors of reproductive outcomes, and examine the effects of follicle-stimulating hor…

AbstractRecurrent pregnancy loss (RPL) and recurrent implantation failure (RIF) are thought to arise from distinct yet partially overlapping causes, with a substantial number of cases associated with immune system alterations. We hypothesiz…

AbstractMammalian oocyte activation is driven by intracellular calcium (Ca2+) oscillations induced by sperm-specific phospholipase C zeta (PLCζ). Sperm PLCζ deficiency is linked to male infertility caused by oocyte activation deficiency. Us…

ABSTRACT: Endometriosis is a chronic inflammatory disease presenting with debilitating symptoms strongly impacting patients' quality of life (QoL). Assessing QoL is crucial for understanding the full patient experience beyond clinical sympt…

ABSTRACT: In women with uterine adenomyosis, bleeding and pain can have a major impact on quality of life. There is clearly a widespread demand for effective long-term medical therapies. The objective of this narrative review was to investi…

While biological and lifestyle determinants of reproductive health are well documented globally, comprehensive data integrating socio-demographic, lifestyle, and health correlates within a contemporary Polish context remain limited. This st…

AbstractPsychological resilience is an adaptive capacity that enables individuals to maintain or regain equilibrium following stress. Infertility treatment represents a significant psychological stressor for many couples. Although higher re…