Chang‐Hai Tsai

No ORCID on file · 11 papers in corpus · active 2001-2008

Study types

  • article 10
  • letter 1

Condition tags

  • endometriosis 11
article 2008
Molecular reproduction and development ·doi:10.1002/mrd.20829

DNA repair systems act to maintain genome integrity in the face of replication errors, environmental insults, and the cumulative effects of age. Genetic variants in DNA repair genes such as X-ray repair cross-complementing group 4 (XRCC4) m…

article 2007
The Chinese journal of physiology

Endometriosis shows some characteristics of malignancy, including local invasion and aggressive spread to distant organs. The pathology of endometriosis may involve a complex interaction among genetic defects, DNA repairing defects and envi…

article 2005
Fertility and Sterility ·doi:10.1016/j.fertnstert.2004.07.977

ObjectiveTo investigate the association of endometriosis with estrogen receptor alpha (ER alpha) and cytochrome P450c17alpha (CYP17) gene polymorphisms in light of the fact that estrogen plays a role in the pathogenesis of endometriosis and…

article 2005
Fertility and sterility ·doi:10.1016/j.fertnstert.2005.02.025

Interleukin (IL)-2 R-627*C homozygote and C allele are related to higher susceptibility to endometriosis. Interleukin-12Rbeta1 codon 378 and IL-18 105 gene polymorphisms are not correlated with endometriosis development.

article 2005
·doi:10.1590/s1415-47572005000500003

Epithelial cadherin (E-cadherin; CDH1) may influence pericellular proteolysis and intracellular signal transduction, which plays an essential part of tumor invasion. In our study we investigated the correlation between CDH1 gene polymorphis…

article 2005
Fertility and Sterility ·doi:10.1016/j.fertnstert.2004.08.032

Epidermal growth factor receptor (EGFR) is a regulator of angiogenesis and mediator of sex steroid-induced cell growth and differentiation. We observed that EGFR gene 2073*T-related genotypes and allele are associated with higher susceptibi…

article 2004
Molecular human reproduction ·doi:10.1093/molehr/gah131

Endometriosis displays features similar to malignancy, ranging from neovascularization to local invasion and aggressive spread to distant organs. The altered vascular-related genes might be related to the development of endometriosis. This …

article 2002
Fertility and Sterility ·doi:10.1016/s0015-0282(01)02938-7

ObjectiveTo evaluate the association between endometriosis and the p53 polymorphism.DesignProspective study.SettingDepartment of gynecology and genetics in a medical center.Patient(s)Women with and without endometriosis.Intervention(s)Women…

letter 2001
Fertility and Sterility ·doi:10.1016/s0015-0282(01)01894-5
article 2001
Journal of assisted reproduction and genetics ·doi:10.1023/a:1016653127262

PurposeWe aimed to investigate if interleukin-1 beta (IL-1 beta) and IL-1 receptor antagonist (IL-1Ra) gene polymorphism could be used as markers of susceptibility in endometriosis.Materials and methodsWomen were divided into two groups: 1)…

article 2001
Journal of clinical laboratory analysis ·doi:10.1002/jcla.1025

p21, an important regulator of the cell cycle, acts as a mediator of the growth-suppressing and -promoting functions of p53. We aimed to investigate the association between codon 31 polymorphisms of p21 gene and endometriosis. Women were di…