T homozygote and allele of epidermal growth factor receptor 2073 gene polymorphism are associated with higher susceptibility to endometriosis and leiomyomas

Hsieh YY, Yao‐Yuan Hsieh, Yao-Yuan Hsieh, Chang CC, Chi-Chen Chang, Tsai FJ, Fuu‐Jen Tsai, Fuu-Jen Tsai, Cheng‐Chieh Lin, Cheng-Chieh Lin, Tsai CH, Chang-Hai Tsai, Chang‐Hai Tsai
Fertility and sterility · 2005 · vol. 83(3) , pp. 796–799 · doi:10.1016/j.fertnstert.2004.08.032 · PMID:15749523 · W2093681187
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The T homozygote and allele of the epidermal growth factor receptor 2073 gene polymorphism are associated with increased susceptibility to endometriosis and leiomyomas.

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Abstract

Epidermal growth factor receptor (EGFR) is a regulator of angiogenesis and mediator of sex steroid-induced cell growth and differentiation. We observed that EGFR gene 2073*T-related genotypes and allele are associated with higher susceptibilities to endometriosis and leiomyoma.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis ErbB Receptors Leiomyoma Polymorphism, Genetic Uterine Neoplasms Endometriosis ErbB Receptors Female Gene Frequency Genetic Predisposition to Disease Genotype Heterozygote Homozygote Humans Leiomyoma Uterine Neoplasms

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References (24)

Cited by (17)

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