T homozygote and allele of epidermal growth factor receptor 2073 gene polymorphism are associated with higher susceptibility to endometriosis and leiomyomas

Hsieh YY, Yao‐Yuan Hsieh, Yao-Yuan Hsieh, Chang CC, Chi-Chen Chang, Tsai FJ, Fuu‐Jen Tsai, Fuu-Jen Tsai, Cheng‐Chieh Lin, Cheng-Chieh Lin, Tsai CH, Chang-Hai Tsai, Chang‐Hai Tsai
Fertility and sterility · 2005 · vol. 83(3) , pp. 796–799 · doi:10.1016/j.fertnstert.2004.08.032 · PMID:15749523 · W2093681187
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The T homozygote and allele of the epidermal growth factor receptor 2073 gene polymorphism are associated with increased susceptibility to endometriosis and leiomyomas.

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Abstract

Epidermal growth factor receptor (EGFR) is a regulator of angiogenesis and mediator of sex steroid-induced cell growth and differentiation. We observed that EGFR gene 2073*T-related genotypes and allele are associated with higher susceptibilities to endometriosis and leiomyoma.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis ErbB Receptors Leiomyoma Polymorphism, Genetic Polymorphism, Genetic Uterine Neoplasms Endometriosis Endometriosis ErbB Receptors ErbB Receptors Female Female Gene Frequency Gene Frequency Genetic Predisposition to Disease Genetic Predisposition to Disease Genotype Genotype Heterozygote Heterozygote

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (24)

Cited by (17)

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