Kaei Nasu
No ORCID on file
· 76 papers in corpus
· active 1999-2026
Study types
- article 54
- dataset 10
- review 7
- other 4
- book-chapter 1
Condition tags
- endometriosis 65
- endometrioma 2
- adenomyosis 2
Top journals
Frequent coauthors
- Hisasshi Narahara 53
- Yuichiro Kawano 28
- Masakazu Nishida 22
- Yoko Aoyagi 22
- Akitoshi Yuge 19
- Kazuharu Kai 18
- Wakana Abe 17
- Mamiko Okamoto 16
- Tomoko Hirakawa 15
- Akitoshi Tsuno 13
article
2026
other
2026
AIM: To investigate the mechanisms of histone deacetylase (HDAC) 10 inhibitors (HDAC10Is) action in endometriosis and the target molecules of HDAC10Is. METHODS: We assessed the effects of HDAC10Is, tucidinostat and TH34, on the proliferati…
article
2025
Objective: The microRNA hsa-miR-132-5p is upregulated in endometriotic cyst stromal cells (ECSCs). We investigate how hsa-miR-132-5p affects the progression of endometriosis. Methods: Normal endometrial stromal cells (NESCs) that have been …
dataset
2021
Read the full review for this Faculty Opinions recommended article: Relugolix, an oral gonadotropin-releasing hormone receptor antagonist, reduces endometriosis-associated pain in a dose-response manner: a randomized, double-blind, placebo-…
other
2021
It is suggested that aberrantly expressed microRNAs are involved in the pathogenesis of endometriosis. Our previous study demonstrated that expression of the microRNA hsa-miR-199a-3p is attenuated in human endometriotic cyst stromal cells (…
review
2021
review
2021
article
2020
dataset
2020
OBJECTIVE: To demonstrate the feasibility of studying exosomes directly from peritoneal fluid, we isolated exosomes from endometriosis patient samples and from controls, and characterized their cargo.DESIGN: Case-control experimental study.…
article
2020
BACKGROUND: A number of microRNAs are aberrantly expressed in endometriosis and are involved in its pathogenesis. Our previous study demonstrated that has-miR-100-5p expression is enhanced in human endometriotic cyst stromal cells (ECSCs). …
article
2019
A number of genes involved in the pathogenesis of endometriosis are silenced by the hypermethylation of their promoter regions. We assessed the effect and mechanism of the DNA demethylating agent 5-aza-2'-deoxycytidine (5-aza-dC) (10 μM) on…
article
2019
Endometriosis exhibits unique characteristics, such as fibrosis, resistance to apoptosis, and promotion of cell proliferation; however, its pathophysiology is not fully understood. Recurrence rates after treatment are high, and the progress…
article
2018
Background: The heritable silencing of genes, without a change in their coding sequence, is due to epigenetic mechanisms. These mechanisms involve DNA methylation, the modification of histone, and non-coding RNA. Disrupting the balance of t…
dataset
2018
article
2017
BACKGROUND: We previously showed that microRNA-503 (miR-503) transfection into endometriotic cyst stromal cells (ECSCs) induced cell cycle arrest at the G0/G1 phase by suppressing cyclin D1. This finding prompted us to evaluate the potentia…
article
2017
dataset
2017
dataset
2017
article
2016
article
2016
To evaluate the involvement of chemokines in the pathogen-esis of endometriosis, we investigated the expression of CXC chemokines in cultured ovarian endometriotic cyst stromal cells (ECSC), endometrial stromal cells with endometriosis (ESC…
review
2016
article
2016
article
2016
STUDY QUESTION: Is the micro-RNA (miRNA) miR-503, downregulated in endometriotic cyst stromal cells (ECSCs) and does this affect the cell cycle, cell proliferation, angiogenesis and contractility of these cells? SUMMARY ANSWER: miR-503 expr…
article
2016
miR-196b targets c-myc and Bcl-2 expression, inhibits proliferation and induces apoptosis in endometriotic stromal cells
article
2016