Role of repressed microRNAs in endometriosis
This review summarizes recent findings on aberrantly repressed microRNAs and their potential roles in the pathogenesis of endometriosis.
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This paper is a review that examines how aberrantly repressed microRNAs (miRNAs) and related epigenetic mechanisms contribute to the pathogenesis of endometriosis, a common estrogen-dependent condition affecting reproductive-age women. It synthesizes recent findings on repressed miRNAs and summarizes their potential roles in endometriosis-associated biological processes, while explicitly framing the evidence as accumulating rather than definitive. A major caveat noted through the review format is that it compiles existing research findings rather than presenting new experimental data or establishing causal relationships. This paper is centrally about endometriosis — specifically the roles of aberrantly repressed microRNAs and epigenetic dysregulation in its pathogenesis.
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Cited by (8)
- Suppression of endometriosis by miRNA-34a via inhibition of matrix metalloproteinase-2: An alternative pathway to impede invasion 2025
- Overexpression of hsa-miR-132-5p in ovarian endometriotic stromal cells promoted acquisition of endometriotic phenotype 2025
- An update on epigenetic mechanisms in endometriosis 2024
- Análise exploratória do miRNoma de células-tronco mesenquimais isoladas de fluxo menstrual de mulheres com endometriose 2023
- Effects of selective inhibition of prostaglandin E2 receptors EP2 and EP4 on the miRNA profile in endometriosis 2022
- Dissecting the miR-451a-Mif Pathway in Endometriosis Pathophysiology Using a Syngeneic Mouse Model: Temporal Expression of Lesion Mif Receptors, Cd74 and Cxcr4 2022
- Advances in Treatment of Endometriosis 2022
- Promising therapeutic targets of endometriosis obtained from microRNA studies 2021
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