A case of undifferentiated carcinoma arising from adenomyosis

Yoko Aoyagi, Kaei Nasu, Haruto Nishida, Saki Aso, Mitsutake Yano, Eiji Kobayashi
In: International Cancer Conference Journal · 2026 · doi:10.1007/s13691-026-00874-2 · W7162210068
article OA: closed CC0
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-11 ⓘ

This case report describes an extremely aggressive undifferentiated carcinoma arising from adenomyosis in a 59-year-old woman, which ultimately led to her death seven months post-surgery.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 ⓘ

This paper reports a case of an extremely aggressive undifferentiated carcinoma arising from adenomyosis in a 59-year-old Japanese woman presenting with fatigue, abdominal fullness, and loss of appetite. Diagnostic workup using contrast-enhanced CT and integrated whole-body 18F-fluorodeoxyglucose positron emission tomography/CT identified multiple para-aortic and pelvic lymph node swellings, while contrast-enhanced MRI showed a 3-cm degenerated intramural uterine tumor; the patient underwent total hysterectomy, bilateral salpingo-oophorectomy, para-aortic and pelvic lymphadenectomy, and partial omentectomy. Pathology diagnosed undifferentiated carcinoma arising from adenomyosis, and despite adjuvant chemotherapy, the patient died 7 months after surgery. As an individual case report, it is limited in generalizability, and the authors note that further investigation of similar cases may clarify clinical features. This paper is centrally about adenomyosis — specifically a case of undifferentiated carcinoma arising from adenomyosis.

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adenomyosis

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