Malignant transformation of adenomyosis is rare, with endometrioid carcinoma being the most common histological type. Herein, we report the first extremely aggressive case of undifferentiated carcinoma arising from adenomyosis. A 59-year-ol…
AIM: To investigate the mechanisms of histone deacetylase (HDAC) 10 inhibitors (HDAC10Is) action in endometriosis and the target molecules of HDAC10Is. METHODS: We assessed the effects of HDAC10Is, tucidinostat and TH34, on the proliferati…
BACKGROUND: Pregnant and postpartum women face an increasing risk of severe complications due to pathophysiological changes, advanced maternal age, obesity, and reproductive technologies. Globally, maternal mortality remains a critical conc…
Both ovarian pregnancy and endometrioma can rupture and cause life-threatening hemoperitoneum. However, little is known about their coexistence. We report the case of a 34-year-old Japanese woman with a life-threatening hemoperitoneum in th…