Maryam Shahhoseini

BACKGROUND: Endometriosis is a benign gynaecological disorder characterised by the presence of endometrial-like tissue outside the uterus. Proliferation of endometrial tissue and neoangiogenesis are essential factors in the development of e…

Endometriosis, a benign gynecological disorder affecting 10-15% of women during their reproductive years, is characterized by the growth of endometrial tissue outside the uterus. Despite its prevalence, the exact pathophysiology of this dis…

BACKGROUND: Endometriosis is a prevalent women's health disorder that lacks a definitive cure. Numerous studies have been conducted to identify the underlying causes of this disease and select the most effective pharmaceutical intervention.…

BACKGROUND: genes and also the binding of ICER to the promoter II of the aromatase gene in endometriosis. MATERIALS AND METHODS: promoter II. RESULTS: were significantly increased in ectopic lesions compared with control endometrial samples…

Laparoscopy is the gold standard for diagnosing endometriosis; however, it is an invasive and costly method. Recent studies offer a non-invasive approach based on extracellular vesicle miRNA. Despite this, no consensus diagnostic biomarker …

Abstract Study question Can evaluation of Cumulus expansion genes (PTGS2, HAS-2, and GREM1) in follicular fluid (FF) and Cumulus cells (CCs) predict oocyte status in women with endometriosis? Summary answer Endometriosis affects the express…

Abstract Study question Does endometriosis affect the expression of Klotho and Telomerase reverse transcriptase (TERT) in Cumulus cells and potentially accelerate oocyte aging? Summary answer Endometriosis significantly reduces Klotho and T…

OBJECTIVE: in eutopic and ectopic endometrial tissues of women with endometriosis compared to the controls. MATERIALS AND METHODS: In this case-control study, 10 women with endometriosis (endometriosis group) and 10 women without endometrio…

BACKGROUND: genes and HOX transcript antisense intergenic RNA (HOTAIR) in mid-luteal phase endometrium in patients with hydrosalpinx before and after salpingectomy. MATERIALS AND METHODS: . RESULTS: mRNA expression levels (P=0.012) were det…

Endometriosis is a common gynecological disease that occurs in between 6 and 10% of women who are at reproductive maturity. The presence of endometrial tissue outside the uterine cavity is the defining characteristic of this disease. Althou…

Increased concentrations of the fibronectin glycoprotein can cause ectopic tissue growth patients with endometriosis and the formation of various cancerous tumors. Furthermore, fibronectin binding to its receptors from the EDA (Extra Domain…

BACKGROUND: Endometriosis, as chronic estrogen-dependent disease, is defined by the presence of endometrial-like tissue outside the uterus. Proliferation of endometrial tissue and neoangiogenesis are critical factors in development of endom…

Additional file 1.

Additional file 1.

Abstract Endometriosis is major gynecological disease that affects over 10% of women worldwide and 30%-50% of these women have pelvic pain, abnormal uterine bleeding and infertility. The cause of endometriosis is unknown and there is no def…

Abstract Endometriosis is major gynecological disease that affects over 10% of women worldwide and 30%-50% of these women have pelvic pain, abnormal uterine bleeding and infertility. The cause of endometriosis is unknown and there is no def…

Abstract Endometriosis is major gynecological disease that affects over 10% of women worldwide and 30%-50% of these women have pelvic pain, abnormal uterine bleeding and infertility. The cause of endometriosis is unknown and there is no def…

Abstract Study question Is epigenetic modifications pattern in DMR region of H19 gene different in endometrial tissues of women with endometriosis in compare to normal endometrium? Summary answer The methylation level in DMR region of H19 g…

Abstract Study question Evolution of the ALX1 and PDHX genes expression and incorporation of H2BK5ac mark on the promoter of these genes in endometriotic tissues versus normal endometrium Summary answer Lower incorporation of H2BK5ac mark i…

OBJECTIVE: promoter polymorphisms and susceptibly to endometriosis and its corolation with mRNA level. MATERIALS AND METHODS: were detected by sequencing. Quantitative polymerase chain reaction (Q-PCR) was carried out to determine MIF expre…