International journal of fertility & sterility

BackgroundPolycystic ovary syndrome (PCOS) is a common endocrine disorder and a leading cause of anovulatory infertility. This study evaluated whether adding vitamin E to a regimen of letrozole, tamoxifen, and estradiol improves ovulation o…

BackgroundPolycystic ovary syndrome (PCOS) is a prevalent endocrine disorder impacting fertility. Controlled ovarian stimulation (COS) is a crucial step during in vitro fertilization (IVF) procedure to enhance oocyte retrieval and embryo ge…

OBJECTIVE: Alcohol sclerotherapy has been shown to reduce endometrioma recurrence and improve ovarian response, including the number of retrieved oocytes and antral follicle count (AFC), compared with surgical cystectomy. This randomized cl…

BackgroundThe prognostic value of borderline and pathological sperm morphology (SM) in infertility treatment remains unclear. This study aims to evaluate the potential impact of SM on clinical pregnancy outcomes following intrauterine insem…

BackgroundRecurrent implantation failure (RIF) is a challenging condition affecting approximately 10% of in vitro fertilization (IVF) patients. Despite extensive investigations, up to half of cases remain unexplained. Immune dysregulation h…

BACKGROUND: Endometriosis is a benign gynaecological disorder characterised by the presence of endometrial-like tissue outside the uterus. Proliferation of endometrial tissue and neoangiogenesis are essential factors in the development of e…

BackgroundHydrosalpinx is a recognized condition affecting the fallopian tubes, which decreases the embryo implantation rate and success in in vitro fertilization (IVF) outcomes. It can manifest detrimental effects through inflammatory cond…

BackgroundThis study aimed to investigate whether uterine cavity flushing combined with antibiotic administration, improves the outcomes of assisted reproductive technology for patients with thin endometrium (<7 mm) associated with chronic …

BackgroundThe success rate of in vitro maturation (IVM) for human oocytes is clinically significant, prompting a focus on optimizing IVM media culture. While various factors have been incorporated to improve outcomes, the role of Ghrelin ho…

BackgroundThis study aims to evaluate the crucial relationship between the follicular distribution pattern (FDP) in polycystic ovaries and its impact on reproductive outcomes. Recognizing these correlations is essential for optimizing assis…

BACKGROUND: Endometriosis is a complex, heterogeneous disease with several genetic and non-genetic pathogenic factors. The phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) pathway may influence bo…

BACKGROUND: Endometriosis is among the leading causes of morbidity in the female population worldwide. Currently, the definite diagnosis of endometriosis depends on laparoscopy as the gold-standard method. Potential biomarkers, such as infl…

BACKGROUND: Endometriosis is a prevalent women's health disorder that lacks a definitive cure. Numerous studies have been conducted to identify the underlying causes of this disease and select the most effective pharmaceutical intervention.…

BACKGROUND: Endometriosis is an estrogen-dependent disease. Cytochrome P450 aromatase which encoded by CYP19A1 is a key enzyme in the pathway of estrogen biosynthesis. cAMP response element (CRE) binding protein (CREB) and cAMP response ele…

BackgroundChromosomal mosaicism, a phenomenon observed in a minority of embryos, showcases its prevalence and inherent unpredictability, leading to variations in embryo mosaic rates across different centers. This research endeavors to asses…

BackgroundDefects in endometrial receptivity are significant factors in infertility and recurrent implantation failure (RIF) during in vitro fertilization (IVF). This study aimed to evaluate the expression levels of steroid hormone receptor…

BACKGROUND: This study aims to determine the effect of laparoscopic surgery for advanced endometriosis on spontaneous pregnancy rates and assisted reproductive techniques (ARTs) in patients with endometriosis. MATERIALS AND METHODS: This r…

BackgroundMyomectomy is commonly performed on women diagnosed with symptomatic uterine leiomyoma(s). This study aimed to evaluate the effects of myomectomy on the serum anti-Müllerian hormone (AMH) levels in women with uterine myoma.Materia…

BackgroundThis research delves into exploring the nexus between lipid profiles and pro-inflammatory cytokines in both blood and follicular fluid (FF). It examines their impact on assisted reproductive technology (ART) outcomes and the prope…

BackgroundLimited data exist regarding the outcomes of frozen-thawed cleavage-stage embryos that undergo extended culture to reach the blastocyst stage. This study aimed to compare the pregnancy outcomes between two approaches: transferring…

BACKGROUND: There is a lack of reliable data or evidence-based protocol for the management of deep infiltrating endometriosis (DIE) lesions in reproductive age women. This study examines ovarian reserves in women who underwent endometriosis…

BackgroundReproductive dysfunctions of polycystic ovary syndrome (PCOS) and blood anti-mullerian hormone (AMH) concentration are significantly influenced by the dietary advanced glycation end products (AGEs). The interplay between AGEs and …

BackgroundThe study was conducted to investigate the effect of dual trigger with gonadotropin-releasing hormone agonist (GnRH-a) and standard dose human chorionic gonadotropin (hCG) on in vitro fertilization/intracytoplasmic sperm injection…

BackgroundThe effectiveness of changing the type of luteal phase support in patients with poor ovarian response (POR) remains unclear based on the available evidence. This study aimed to compare the effectiveness of various luteal phase sup…

BackgroundCynodon dactylon traditionally employed or treating hormonal problems in women. Therefore, this study aimed to assess the effect of C. dactylon hydroalcoholic extract of on letrozole-induced polycystic ovary syndrome (PCOS) in adu…