Keith A. Hansen

Dr. Hansen is from the Department of Obstetrics and Gynecology at the University of South Dakota School of Medicine, Sioux Falls, SD; e-mail: [email protected]. Financial Disclosure The author did not report any potential conflicts of inter…

Abstract: Endometriosis remains a cause of significant morbidity in reproductive-aged women resulting in pelvic pain, pelvic masses and infertility. Endometriosis is defined as the presence of endometrial glands and stroma outside of their …

The purpose of this study was to test the hypothesis that specific macrophage-secreted cytokines cause gene expression changes in endometrial stromal cells that reproduce the effects of macro-phages in the development of endometriosis. Telo…

This month, we focus on current research in endometriosis. Dr. Hansen discusses six recent publications, and each is concluded with a “bottom line” that is the take-home message. The complete reference for each can be found in Box 1 on this…

Endometriosis is a common cause of morbidity in women with an unknown etiology. Studies have demonstrated the familial nature of endometriosis and suggest that inheritance occurs in a polygenic/multifactorial fashion. Studies have attempted…

Endometriosis, a common cause of morbidity in reproductive-age females, results in pelvic pain and infertility. Endometriosis-associated pain can be approached with surgical or medical therapies. Conservative surgery maintains reproductive …

Immune system cells and cells of the endometrium have long been proposed to interact in both physiological and pathological processes. The current study was undertaken to examine communication between cultured monocytes and endometrial stro…

Endometriosis, a common cause of morbidity in reproductive age females, results in pelvic pain and infertility. Effective, evidence-based treatments of endometriosis-associated infertility include conservative surgical therapy and assisted …

OBJECTIVE: To use DNA microarray technology to examine differential gene expression in uterine endometrium versus endometriosis implants. DESIGN: Pilot study. SETTING: Volunteers in an academic research environment. PATIENT(S): Premenopa…