Ruswana Anwar

Background: Adenomyosis is a major cause of chronic pelvic pain in women of reproductive age and significantly affects quality of life. Identifying biomarkers associated with pain mechanisms may improve understanding of disease pathophysiol…

Endometriosis is an enigmatic disease affecting approximately 10% of the population. This unique disease is often chronic and characterized by inflammation. Even though endometriosis and its related disease, adenomyosis, are benign tumors, …

Amadea Ivana Hartanto,1 Dian Tjahyadi,2 Ruswana Anwar,2 Fridya Wulandari,2 Eunike Febe Febriani,3 Siti Shofiah Syahruddin3 1Department of Obstetrics and Gynecology, Faculty of Medicine, Padjadjaran University, Dr. Hasan Sadikin General Hosp…

Abstract: Endometriosis is an estrogen-dependent inflammatory disorder that may be influenced by bisphenol A (BPA), an endocrine-disrupting chemical commonly found in food-contact plastics. BPA has been implicated in altered steroidogenesis…

Background: Endometriosis is a chronic gynecological disorder characterized by the presence of endometrium-like tissue outside the uterine cavity. It is most commonly found in the pelvic organs but may also occur in extrapelvic sites, inclu…

Dian Tjahyadi, Aisyah Shofiatun Nisa, Hartanto Bayuaji, Gatot Nyarumenteng Adhipurnawan Winarno, Ruswana Anwar Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran – Dr. Hasan Sadikin General Hospital, Ban…

INTRODUCTION: Endometriosis is a major gynecologic health issue affecting ~10% of women and girls of reproductive age worldwide. Despite its high prevalence, no curative treatment exists. Early diagnosis and treatment are critical to preven…

INTODUCTION: Endometriosis is a chronic inflammatory condition characterized by the presence of endometrial tissue outside the uterus, leading to pelvic pain and infertility. It affects approximately 10% of women of reproductive age. Endome…

Introduction: The triple-step method, which comprises transvaginal ultrasound-guided aspiration (TUGA) of cyst fluid, three cycles of a gonadotropin-releasing hormone (GnRH) agonist, and laparoscopic cystectomy, has been proposed for managi…

Background: Endometriosis is a chronic inflammatory condition, causing severe pelvic pain, organ dysfunction, infertility, and mental health issues. Ovarian reserve, indicating the quantity and quality of a woman's oocytes, is negatively af…

• Higher VAS scale is observed in those with adenomyosis. • Adenomyosis is associated with low progesterone environment. • IL-6, VEGF and COX-2 is found increased in adenomyosis. • Heightened inflammatory profile highlights the pro-inflamma…

Systemic lupus erythematosus predominantly affects women of all ages, particularly targeting those of reproductive age, and can increase the risk of adverse pregnancy outcomes, including uterine atony, which is rarely documented. This case …

BACKGROUND: Endometriosis involves the presence of endometrial-like tissue outside the uterus, driven by inflammatory pathways including elevated interleukin-32 and vascular endothelial growth factor. One potential anti-inflammatory agent i…

OBJECTIVE: This study aimed to investigate the levels of chitinase-3-like protein-1 (CHI3L1), matrix metalloproteinase-9 (MMP-9), and monocyte chemoattractant protein-1 (MCP-1) in adenomyosis, as compared to normal myometrial tissue. These …

Introduction: Abdominal pain is a diagnostic problem that requires immediate care and treatment for surgeons and gynecologists. The causes of abdominal pain in women of childbearing age range from benign and temporary to potentially life th…

BACKGROUND: Low birth weight (LBW) is a risk factor associated with endometriosis. Our study aimed to analyze the risk of endometriosis in women with a LBW history and the relationships of progesterone receptor B (PR-B) gene promoter methyl…

Objectives: This study aimed to examine the effect of a laparoscopic cystectomy on ovarian reserve assessed by measuring the levels of serum follicle stimulating hormone (FSH) and anti-Müllerian hormone (AMH). Materials and Methods: This pr…

Tujuan : Kegiatan pengabdian masyarakat ini bertujuan untuk untuk menganalisis tingkat pengetahuan dismenore yaitu dismenore primer dan sekunder dengan memberikan solusi melalui penyuluhan di Kota Bandung. Metode : Kegiatan pertama adalah k…

Tujuan: Kegiatan pengabdian masyarakat ini bertujuan untuk untuk menganalisis tingkat pengetahuan dismenore yaitu dismenore primer dan sekunder dengan memberikan solusi melalui penyuluhan di Kota Bandung. Metode: Kegiatan pertama adalah kun…

Adenomyosis is a pathological condition characterized by the presence of endometrial glands and stroma within the myometrium. Endometrial like cells development was influenced by local inflammatory reactions, increases local estradiol due t…

Objectives: This study aimed to measure the vascular endothelial growth factor (VEGF) expression in menstrual effluent from patients with endometriosis compared to non-endometriosis through immunocytochemical methods. We also measured the d…

Terdapat perubahan fenotip molekuler endometrium eutopik pada endometriosis berupa perubahan ekspresi gen, respon terhadap hormone steroid, peningkatan marker inflamasi dan molekul adesi seluler, penurunan indeks apoptosis dan kapasitas des…

Aim: To identify the correlation between mRNA expression of aromatase, 17β-HSD2 level of TGF-β1 and stage of endometriosis. Methods: Case control study was done on 80 patients divided by 40 endometriosis patients and 40 patients as control.…

Objectives: To analyze the association between Ki-67 expression with the cyst size and stage of endometriosis, and the correlation strength between them. Methods: A cross-sectional analytic observational study involving 56 paraffin blocks f…