Asmarinah Asmarinah

BACKGROUND: The cytokine chemokine ligand 16 (CXCL16) plays an important role in the pathophysiology of endometriosis by regulating the inflammatory response and contributing to the pain-associated endometriosis. Despite this, the impact of…

Endometriosis is gynecology disease that still needs advance knowledge to develop best treatment for enhancing the best quality of patient life. It is characterized by forming the endometrium tissue outside the uterus and happened approxima…

Transient Receptor Ankyrin Member 1 (TRPA1) is an ion channel family protein that regulates pain sensation through sensory neurons' activity. This study's purpose to analyzes the DNA methylation and mRNA expression level of the TRPA1 gene i…

OBJECTIVE: Endometriosis is a multifactorial disease that affects 10% of women of childbearing age. Its development is known to be related to the MMP-2 gene. Specifically, the expression of MMP-2 is increase in endometriosis. The aim of thi…

Abstract It has been known that the EGFR have the role for regulation the cytoskeleton activity and its expression increased in endometriosis tissue. The aim of this study was to evaluate the DNA methylation of the EGFR gene that might caus…

Focal adhesion molecules involve in cellular migration, attachment, and play a role in endometriosis pathomechanisms. Recent studies showed that the expression of RAC1, a gene encoded focal adhesion molecule, was predominantly found in endo…

Abstract Endometriosis is characterized by the presence of endometrial-like tissues located outside the uterine cavity. The expression of focal adhesion genes including FN1 gene increased in endometriosis. Epigenetic factors play a role in …

Abstract Endometriosis is a common, benign, oestrogen-dependent, chronic gynaecological disorder associated with pelvic pain and infertility. Increasing of P2X3 receptors induced sensitization of pain in endometriosis patients. Epigenetic m…

Endometriosis is a disease characterized by implantation of endometrial-like tissues outside the uterus. Until now, its pathogenesis of remains unclear. Previous studies have suggested a possible role of epigenetics in endometriosis. The pu…

Endometriosis is a multifactorial disease in which genetic and environmental factors interact causing its pathogenesis. The aim of this study was to investigate the expression pattern of estrogen receptor α (ERα) and β (ERβ) in endometriosi…

Endometriosis, a chronic inflammatory disorder, is characterized by the presence of hormone-responsive, endometrial-like tissue outside of the uterine inner wall, such as in the peritoneum and ovaries. Progesterone (P) resistance, due to al…

Endometriosis, defined as the growth of endometrial-like tissue outside the uterus, leads to the emergence of chronic inflammatory reactions, which are influenced by the plasminogen activator systems that are known to play a role in fibrino…

Objective: To investigate the HOXA11 gene profile on endometriosispatients with infertility in Indonesia.Methods: This cross sectional study was conducted in Dr. CiptoMangunkusumo Hospital from July 2015- June 2016. The subjectswere endomet…

Background Endometriosis and infertility have been shown to be related to one another. The mechanisms that explain this phenomenon are not fully understood. One of the possible mechanisms of infertility in endometriosis patients is failure …