OBJECTIVE: To study altered hemopexin concentrations in peritoneal fluid (PF) samples from patients with endometriosis. Recent data implicate a role of altered iron metabolism in endometriosis patients. Hemopexin is the major transport prot…
Endometriosis is determined by local and systemic proinflammatory dysregulation and therefore differential protein expression in peritoneal fluid (PF). Of highest interest is lesion formation and the establishment and persistence of endomet…
Purpose Several markers for diagnosis of endometriosis that have been tested in clinical approaches so far lack in both sensitivity and specificity. Therefore, it is conceivable that a need exists to perform a cluster analysis in which the …
This study investigated the possible use of CCR1 mRNA measurement in peripheral blood leukocytes in combination with measurements of monocyte chemotactic protein-1 (MCP-1) and CA125 protein in serum as a diagnostic test for endometriosis.Th…
OBJECTIVE: To evaluate whether distinct patterns of serum proteins in symptomatic women are of value to predict endometriosis before laparoscopy. DESIGN: Prospective exploratory cohort study. SETTING: Tertiary care center. PATIENT(S): A …
We investigated the expression of the cognate chemokine receptor 1 (CCR1) messenger ribonucleic acid, a G-protein-coupled cognate chemokine receptor with high affinity for RANTES (Regulated upon Activation, Normal T cells Expressed and Secr…
The authors demonstrate expression of the vitamin D receptor (VDR) and its hydroxylases in the endometrium and ovaries of women with and without endometriosis and endometrial or ovarian cancer. Immunohistochemistry showed strong staining of…
Hintergrund: Endometriose stellt neben Malignomen des weiblichen Genitale die häufigste Ursache für organdestruktives Wachstum dar und ist gekennzeichnet durch das Vorkommen von endometrialem Gewebe außerhalb des Cavum uteri. Für die Etabli…
BACKGROUND: Aromatase is the key enzyme in the process of estrogen biosynthesis from the precursor androgen. Recently, aromatase has been found to be aberrantly expressed in eutopic endometrium of patients suffering from endometriosis. This…