Rare case of endometrioid adenocarcinoma arising from cystic adenomyosis

Mayuyo Mori, Mori M, Furusawa A, Akiko Furusawa, Nao Kino, Kino N, Masaya Uno, Uno M, Ozaki Y, Yoshikazu Ozaki, Toshiharu Yasugi, Yasugi T
Journal of Obstetrics and Gynaecology Research · 2014 · vol. 41(2) , pp. 324–328 · doi:10.1111/jog.12513 · PMID:25331723 · W1511778084
Case report OA: bronze CC0 ⤵ 12 in-corpus citations
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This case report describes a 67-year-old woman with endometrioid adenocarcinoma arising from cystic adenomyosis, highlighting the risk of malignant transformation in cystic adenomyoma.

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Abstract

Few reports on malignant transformation of adenomyosis are available, and endometrioid adenocarcinoma arising from cystic adenomyosis is further rarely reported. We report a case of a 67-year-old asymptomatic woman who was referred to our hospital for evaluation of a cystic lesion in the pelvis, which had been diagnosed as cystic degeneration of leiomyoma for 3 years. Magnetic resonance imaging revealed a cystic mass measuring 11 cm in diameter, which was contiguous with uterine myometrium. The lesion contained solid areas enhanced on gadolinium-enhanced T1 -weighted imaging. Transabdominal simple total hysterectomy with bilateral salpingo-oophorectomy was performed. Pathological examination revealed endometrioid adenocarcinoma arising from cystic adenomyosis. The patient underwent six courses of adjuvant combination chemotherapy with paclitaxel and carboplatin. No metastasis or recurrence has been demonstrated for 16 months following surgery. Our case demonstrates that cystic adenomyoma possesses the risk of malignant transformation, indicating the importance of long-term follow-up with imaging examination.

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Condition tags

adenomyosis

MeSH descriptors

Adenomyoma Carcinoma, Endometrioid Endometrial Neoplasms Adenomyoma Adenomyoma Aged Aged Carcinoma, Endometrioid Carcinoma, Endometrioid Carcinoma, Endometrioid Cell Transformation, Neoplastic Cell Transformation, Neoplastic Endometrial Neoplasms Endometrial Neoplasms Endometrial Neoplasms Female Female Humans Humans

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (14)

Cited by (12)

Source provenance

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