Rare case of endometrioid adenocarcinoma arising from cystic adenomyosis

Mayuyo Mori, Akiko Furusawa, Nao Kino, Masaya Uno, Yoshikazu Ozaki, Toshiharu Yasugi
Journal of Obstetrics and Gynaecology Research · 2014 · vol. 41(2) , pp. 324–328 · doi:10.1111/jog.12513 · PMID:25331723 · W1511778084
article OA: bronze CC0 ⤵ 12 in-corpus citations
🔓 Open OA copy View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This case report describes a 67-year-old woman with endometrioid adenocarcinoma arising from cystic adenomyosis, highlighting the risk of malignant transformation in cystic adenomyoma.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Few reports on malignant transformation of adenomyosis are available, and endometrioid adenocarcinoma arising from cystic adenomyosis is further rarely reported. We report a case of a 67-year-old asymptomatic woman who was referred to our hospital for evaluation of a cystic lesion in the pelvis, which had been diagnosed as cystic degeneration of leiomyoma for 3 years. Magnetic resonance imaging revealed a cystic mass measuring 11 cm in diameter, which was contiguous with uterine myometrium. The lesion contained solid areas enhanced on gadolinium-enhanced T1 -weighted imaging. Transabdominal simple total hysterectomy with bilateral salpingo-oophorectomy was performed. Pathological examination revealed endometrioid adenocarcinoma arising from cystic adenomyosis. The patient underwent six courses of adjuvant combination chemotherapy with paclitaxel and carboplatin. No metastasis or recurrence has been demonstrated for 16 months following surgery. Our case demonstrates that cystic adenomyoma possesses the risk of malignant transformation, indicating the importance of long-term follow-up with imaging examination.

My notes (saved in your browser only)

Condition tags

adenomyosis

MeSH descriptors

Adenomyoma Carcinoma, Endometrioid Endometrial Neoplasms Adenomyoma Aged Carcinoma, Endometrioid Carcinoma, Endometrioid Cell Transformation, Neoplastic Endometrial Neoplasms Endometrial Neoplasms Female Humans

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (14)

Cited by (12)

Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:18:15.805398+00:00
License: CC0 · commercial use OK