Endometriosis and Infertility Management

In: Türk Üreme Tıbbı ve Cerrahisi Dergisi · 2018 · vol. 2(2) , pp. 60–68 · doi:10.24074/tjrms.2016-54242 · W2900714220
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Endometriosis is an estrogen-dependent inflammatory condition characterized by ectopic endometrial-like tissue in the uterus, often causing severe pain and infertility, and affecting 6-10% of women of reproductive age.

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This paper reviews how endometriosis contributes to infertility, describing mechanisms involving disturbances in pelvic anatomy and processes spanning folliculogenesis, fertilization, and/or implantation. It outlines management approaches used in infertility practice, including laparoscopic surgery, controlled ovarian stimulation with intrauterine insemination, and assisted reproductive technologies. The authors state that there is no role for medical treatment in infertility management when endometriosis patients have no concomitant pain, and they emphasize a key caveat that surgery may irreversibly decrease ovarian reserve. This paper is centrally about endometriosis — specifically its management in infertility and the factors influencing treatment decisions.

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Abstract

TJRMS 2018;2(2) 60 ndometriyozis uterus dnda ektopik endometrium benzeri doku varl ile karakterize strojen baml ve inflamatuar bir durumdur. Sklkla ciddi ve kronik ar ve infertilite ile ilikilidir. 1 Esas olarak pelvik periton, overler ve rektovajinal septum tutulur. Nadiren de diyafram, plevra ve perikard tutulumu grlebilir. reme andaki kadnlarn yaklak %6 ile 10'unda endometriyozis ile karlalr. Tubal sterilizasyon yaplan hastalarn %1-7'sinde rastlantsal endometriyozis tespit edilir.
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ABSTRACT Endometriosis is a frequently encountered problem in infertility practice. Although the pathogenesis has not been well understood yet, the mechanisms of infertility include disturbances in pelvic anatomy, folliculogenesis, fertilization and/or implantation. Laparoscopic surgery, controlled ovarian stimulation and intrauterine insemination and assisted reproductive technologies are used in the management of patients with endometriosis and infertility. There’s no place for medical treatment in infertility management of cases without concomitant pain. Clinicians should be very cautious when deciding surgery for these patients. There’s risk of irreversibly decreasing ovarian reserve during endometriosis surgery. While planning infertility treatment in patients with endometriosis decision should be made by taking into consideration the age of patient, duration of infertility, presence of accompanying pelvic pain and disease stage.

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Condition tags

endometriosisinfertility

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last seen: 2026-06-04T00:00:01.174412+00:00
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