Efficacy of isotopic 13CO2 laser laparoscopic evaporation in the treatment of infertile patients with minimal and mild endometriosis: A life table cumulative pregnancy rates study
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This life table study evaluated the cumulative pregnancy rates in infertile patients with minimal and mild endometriosis treated with isotopic 13CO2 laser laparoscopic evaporation.
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Abstract
Study objectiveTo assess the efficacy of 13CO2 laser laparoscopy in treating infertile women with minimal to mild endometriosis according the American Fertility Society classification in terms of pregnancy rates.DesignProspective study.SettingMedical school-affiliated hospital.PatientsOne hundred seventy-six women whose infertility was associated with minimal or mild endometriosis diagnosed by laparoscopy.InterventionsThe patients were treated with one of four methods: 49 underwent operative laparoscopy with newly developed 13CO2 laser vaporization and/or resection; 45 were treated by operative laparoscopy with simple monopolar electrocoagulation; 43 who had undergone only diagnostic laparoscopy did not receive any treatment; and 39 received danazol 800 mg/day for 3 months after diagnostic laparoscopy.Measurements and main resultsEstimated cumulative pregnancy rates using life table analyses were indicators of treatment of success and compared among the treatments. A subgroup of 111 patients considered to have endometriosis as the only major infertility factor were also evaluated and compared among treatment options. Pregnancy rates in the CO2 laser laparoscopy group were significantly higher than in the other three groups and in endometriosis-only subset.ConclusionsAdvanced laparoscopic surgery with the CO2 laser can be more efficient than other modalities in treating infertile women with minimal to mild endometriosis in terms of pregnancy rates. It appears that in experienced hands, laser laparoscopy has more favorable results than the other treatments.
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Cited by (18)
- Endometriosis 2025
- Efficacy of ten interventions for endometriosis: A network meta‐analysis 2019
- Endométriose minime à légère : résultats du traitement chirurgical sur la douleur et l’infertilité et modalités techniques. Quelles stratégies thérapeutiques ? RPC Endométriose CNGOF-HAS 2018
- Female Reproductive Pathology 2018
- Endometriosis and Infertility Management 2018
- Surgery for endometriosis-associated infertility: do we exaggerate the magnitude of effect? 2015
- Endometriosis and Infertility: How and When to Treat? 2014
- Руководство европейского общества репродукции человека и эмбриологии (ESHRE): менеджмент женщин с эндометриозом 2014
- Laparoscopic surgery for subfertility associated with endometriosis 2010
- Infertilidad y endometriosis 2007
- Accuracy of diagnostic laparoscopy in the infertility work-up before intrauterine insemination 2003
- Laparoscopic surgery for subfertility associated with endometriosis 2002
- The efficacy of medical and surgical treatment of endometriosis-associated infertility: arguments in favour of a medico-surgical aproach 2002
- Lasers in Gynaecology 2002
- Diagnostic et suivi de l’endométriose en consultation : nouveautés 2001
- Medical and Surgical Therapies for Pain Associated with Endometriosis 2001
- Laparoscopic ablation is not necessary for minimal or mild lesions in endometriosis associated subfertility 2001
- Today's treatments: how do you choose? 1999
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