Estrogen receptor dinucleotide repeat polymorphism is associated with minimal or mild endometriosis
Observational
OA: bronze
CC0
⤵ 18 in-corpus citations
AI-generated summary
A dinucleotide repeat polymorphism in the estrogen receptor gene was found to be associated with minimal or mild endometriosis in this study.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
The present study was designed to explore the association between estrogen receptor-alpha gene polymorphism and the risk of endometriosis by investigating the frequency of PvuII, XbaI, and thymine-adenine (TA) repeat polymorphisms in patients with and without endometriosis in a Korean population. Although there was no significant difference in the allele distribution and frequency of either PvuII or XbaI polymorphisms between endometriosis patients and control subjects, patients with stage I/II endometriosis showed a higher incidence of alleles with fewer (TA)n repeats (12-15 repeats) compared with controls.
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood (2-hop)
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]
References (9)
- Association of estrogen receptor gene polymorphisms with endometriosis via openalex
- Clinical aspects of endometriosis via openalex
- Peritoneal endometriosis, ovarian endometriosis, and adenomyotic nodules of the rectovaginal septum are three different entities via openalex
- Polymorphisms in the estrogen receptor beta gene but not estrogen receptor alpha gene affect the risk of developing endometriosis in a Japanese population via openalex
- Possible involvement of arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1 genes in the development of endometriosis via openalex
- W6636516040 via openalex
- W1990034002 via openalex
- W2105981541 via openalex
- W1616724830 via openalex
Cited by (17)
- Sex hormone-related polymorphisms in endometriosis and migraine: A narrative review 2022
- Polymorphisms and endometriosis: a systematic review and meta-analyses 2019
- Relationships between vitamin D receptor genetic polymorphisms and endometriosis in Korean women 2019
- Androgen receptor cytosine, adenine, and guanine trinucleotide repeat polymorphism in Korean patients with endometriosis: A case-control study 2017
- Understanding the role of epigenomic, genomic and genetic alterations in the development of endometriosis (review) 2014
- Sex Steroids and Endometriosis 2014
- Associations between Estrogen Receptor Gene Polymorphisms and Endometriosis 2013
- Pathogenesis of endometriosis: the role of genetics, inflammation and oxidative stress 2012
- Mitochondria DNA polymorphisms are associated with susceptibility to endometriosis 2011
- Endometriosis and headache 2011
- Genetic variation in the sex hormone metabolic pathway and endometriosis risk: an evaluation of candidate genes 2011
- Association of peroxisome proliferator-activated receptor-gamma 2 Pro12Ala polymorphism with advanced-stage endometriosis 2010
- Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis 2008
- Intron 1 and exon 1 alpha estrogen receptor gene polymorphisms in women with endometriosis 2008
- Common genetic influences underlie comorbidity of migraine and endometriosis 2008
- Endometriosis and genetic polymorphisms 2007
- Estrogen receptor alpha-351 XbaI*G and -397 PvuII*C-related genotypes and alleles are associated with higher susceptibilities of endometriosis and leiomyoma 2006
Source provenance
- europepmc
- last seen: 2026-10-15T06:08:49.021275+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:03:24.829172+00:00
License: CC0
· commercial use OK