A bélendometriosis miatt végzett műtétek hatása a fertilitásra

Réka Brubel, Noémi Dobó, Noémi Csibi, Annamária Kövesdi, Szabolcs Máté, Nándor Ács, Péter Lukovich, Ákos Murber, Attila Bokor
Orvosi hetilap · 2019 · vol. 160(41) , pp. 1633–1638 · doi:10.1556/650.2019.31514 · PMID:31587576 · W2980092107
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Abstract

Abstract: Introduction: Bowel endometriosis is when endometrial-like tissue penetrates the bowel serosa, or it reaches the subserous neurovascular plexus. The effect of surgery for colorectal endometriosis on infertility and pregnancy is not fully proven. Aim: The aim of the present study was to analyse the pregnancy outcome and mode of delivery of patients who underwent ’nerve sparing’ anterior resection of the colon. Method: Between 2009 and 2017, we operated 121 patients with bowel endometriosis, and built up a prospective database where we assessed their wish of pregnancy, the way of the conception, pathologies during pregnancy and mode of delivery. Statistical analysis: The relationship between endometriosis and pregnancy pathologies was tested by a χ 2 probe and Fisher’s exact test, additionally the odds ratio (OR) and 95% confidence interval (CI) were determined. For p<0.05, the result was considered significant. Results: Out of 121 bowel endometriosis patients, 48 (39.6%) women got pregnant, 37 (30.5%) of them with in vitro fertilisation. The control group was built from patients who underwent in vitro fertilisation because of andrological factors. We found that women with endometriosis have a significantly higher risk for praeeclampsia (p = 0.023) and placenta praevia (p = 0.045) during pregnancy. Conclusions: Our study is a unique description of pregnancy outcome and mode of delivery after surgery for bowel endometriosis, which, despite the small number of cases, has yielded similar results to the previous multicentric studies. Orv Hetil. 2019; 160(41): 1633–1638.

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Condition tags

mesh:D004715endometriosisbowel_endometriosisinfertility

MeSH descriptors

Endometriosis Fertility Fertilization in Vitro Infertility, Female Endometriosis Endometriosis Female Fertility Fertilization in Vitro Humans Infertility, Female Placenta Previa Placenta Previa Pre-Eclampsia Pre-Eclampsia Pregnancy Pregnancy Outcome Pregnancy Outcome Pregnancy Rate Prospective Studies

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