Associations between C-reactive protein-triglyceride glucose index and Endometriosis: the NHANES 1999-2006

Yanan Ren, Ren Xu, Junqin Zhang, Ying Jin, Di Zhang, Yazhuo Wang, Luyang Su
In: Research Square · 2024 · doi:10.21203/rs.3.rs-5181764/v1 · W4405456808
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-06 ⓘ

This study analyzed NHANES data from 1999-2006 and found that higher C-reactive protein-triglyceride glucose index (CTI) levels were positively associated with the prevalence of endometriosis.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-06 ⓘ

This study examined whether the C-reactive protein–triglyceride glucose index (CTI), defined from serum CRP, fasting triglycerides, and fasting glucose, is associated with endometriosis using 2,235 women aged 20–50 years from NHANES 1999–2006. Using multivariate logistic regression (with additional adjustment for sociodemographic factors, BMI, smoking, hypertension/diabetes, alcohol, and oral contraceptive use), CTI was higher in women reporting endometriosis, and CTI showed a statistically significant positive association with endometriosis prevalence, including a higher prevalence across CTI tertiles and a nonlinear positive relationship modeled by restricted cubic splines. The paper’s key limitation is that endometriosis status was based on self-report of a clinician diagnosis rather than objective clinical confirmation. This paper is centrally about endometriosis—assessing the association between CTI (inflammation/insulin-resistance biomarker) and endometriosis prevalence in US women using NHANES data.

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Condition tags

endometriosis

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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