Adenomyosis decreases the live birth rate but may not affect perinatal outcomes in assisted reproductive cycles
article
OA: closed
CC0
⤵ 4 in-corpus citations
AI-generated summary
This study found that adenomyosis decreased live birth rates in ovum donation cycles but did not significantly affect perinatal outcomes like delivery mode, gestational age, or newborn weight.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
OBJECTIVE: To determine if uterine adenomyosis is associated with worse perinatal outcomes in ovum donation assisted reproductive treatment cycles. MATERIALS AND METHODS: A multicenter and retrospective cohort study in which a total of 3307 patients undergoing an ovum donation cycle in 2018-2019 were included and divided into two groups: adenomyosis (n = 179) and controls (n = 3128). Clinical, obstetrical, and perinatal outcomes were analyzed. RESULTS: A lower live birth rate per embryo transfer was observed in women diagnosed with adenomyosis versus control women: 67/179 (37%) versus 1560/3128 (49.9%), respectively (odds ratio 0.6, 95% confidence interval 0.43-0.83, P = 0.002). There was no statistically significant difference in childbirth delivery method (vaginal versus cesarean section) between the adenomyosis and control groups. Mean gestational age at the time of delivery, newborn length and weight, and incidences of low birth weight, preterm birth, and admission to the neonatal intensive care unit did not differ between the two groups. In addition, in vitro fertilization and perinatal outcomes were similar in patients with diffuse compared with focal adenomyosis. CONCLUSIONS: Adenomyosis affects clinical but may not affect perinatal outcomes in ovum donation cycles.
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (24)
- Aberrant expression of glutathione peroxidase in eutopic and ectopic endometrium in endometriosis and adenomyosis via openalex
- Adenomyosis and adverse perinatal outcomes: increased risk of second trimester miscarriage, preeclampsia, and placental malposition via openalex
- Adenomyosis: epidemiological factors via openalex
- Adenomyosis in infertile women: prevalence and the role of 3D ultrasound as a marker of severity of the disease via openalex
- Clinical outcomes of infertility treatment for women with adenomyosis in Japan via openalex
- Complications and outcomes of pregnant women with adenomyosis in Japan via openalex
- Effect of Adenomyosis on In Vitro Fertilization/Intracytoplasmic Sperm Injection Outcomes in Infertile Women: A Retrospective Cohort Study via openalex
- Expression of Aromatase Cytochrome P450 Protein and Messenger Ribonucleic Acid in Human Endometriotic and Adenomyotic Tissues but not in Normal Endometrium1 via openalex
- High endometrial aromatase P450 mRNA expression is associated with poor IVF outcome via openalex
- HOXA10 expression is decreased in endometrium of women with adenomyosis via openalex
- Leukemia inhibitory factor is dysregulated in the endometrium and uterine flushing fluid of patients with adenomyosis during implantation window via openalex
- Pregnancy outcome in women with endometriosis achieving pregnancy with IVF via openalex
- Reproductive, obstetric, and perinatal outcomes of women with adenomyosis and endometriosis: a systematic review and meta-analysis via openalex
- Risk of preterm birth, low birthweight and small‐for‐gestational‐age infants in pregnancies with adenomyosis: A cohort study of the Japan Environment and Children's Study via openalex
- Structural abnormalities of the uterine wall in women with endometriosis and infertility visualized by vaginal sonography and magnetic resonance imaging via openalex
- The distribution of immune cells and macrophages in the endometrium of women with recurrent reproductive failure. II: adenomyosis and macrophages via openalex
- The impact of adenomyosis on the outcome of IVF–embryo transfer via openalex
- Ultrasonography compared with magnetic resonance imaging for the diagnosis of adenomyosis: correlation with histopathology via openalex
- Ultrasound diagnosed adenomyosis has a negative impact on successful implantation following GnRH antagonist IVF treatment via openalex
- Uterine adenomyosis and in vitro fertilization outcome: a systematic review and meta-analysis via openalex
- W2616269988 via openalex
- W2042196434 via openalex
- W2515052691 via openalex
- W2753073405 via openalex
Cited by (4)
- Systematic review and meta‐analysis of adverse pregnancy outcomes with different types of adenomyosis 2025
- Adenomyosis, especially in its focal nature, hampers implantation and live birth rate after single euploid embryo transfer 2024
- Different subtypes of ultrasound‐diagnosed adenomyosis and in vitro fertilization outcomes: A systematic review and meta‐analysis 2023
- Meta-Analysis on the Therapeutic Effectiveness of Dienogest plus GnRH Agonist in Treating Adenomyosis and Its Related Obstetric Risk Factors 2021
Source provenance
- europepmc
- last seen: 2026-06-04T01:30:01.192114+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-06-04T00:34:54.200900+00:00
License: CC0
· commercial use OK