The biological basis of medical treatment of endometriosis

Venturini PL, Pier Luigi Venturini, P L Venturini, Semino A, A Semino, Loris De Cecco, De Cecco L, L De Cecco
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 1995 · vol. 9(3) , pp. 259–266 · doi:10.3109/09513599509160455 · PMID:8540297 · W2110411664
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⚙ AI-generated summary by claude@2026-06, 2026-06-11 ⓘ

This paper analyzes the morphology, implant activity, and immune involvement of endometriosis to better define medical management, given variable disease presentation, treatment limitations, and recurrence after interventions.

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Abstract

Efficacy of medical treatment for the management of endometriosis has been documented in several trials, but clinical results cannot always be maintained after the suspension of treatment. Surgical treatment, either laparotomic or laparoscopic, is affected by up to 20% in the recurrence of clinical symptoms after long-term follow-up. The appearance of endometriosis is heterogeneous, its functional status is variable and could lack hormone responsiveness. After medical, surgical or combined treatment the persistence of the failure of defence mechanisms accounts for the recurrence of disease. Unfortunately, all schemes to classify stages of endometriosis have so far failed to identify manifestations of the disease that respond in a predictable way to specific treatments. An analysis of the morphological appearance, implant biological activity and immune system involvement might better define the roles for medical management of endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Female Hormones Hormones Humans

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (44)

Source provenance

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License: CC0 · commercial use OK