Antigenic differences between the endometrium of women with and without endometriosis.

D Garza, Subbi Mathur, S Mathur, Melissa Dowd, M M Dowd, L F Smith, H. Oliver Williamson, H O Williamson
The Journal of reproductive medicine · 1991 · vol. 36(3) , pp. 177–82 · PMID:2030493 · W2426012558
article OA: closed CC0 ⤵ 23 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

Patients with endometriosis or uterine leiomyomata had significantly higher serum antibody titers against endometrial and implant antigens from women with endometriosis and two women with leiomyomata compared to controls.

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Abstract

Serum and peritoneal fluid from 12 women with endometriosis, 4 women with uterine leiomyomata and 6 fertile women without endometriosis (controls) and serum from 4 women with adenomyosis were tested with a passive hemagglutination assay for antibodies against endometrium from all the controls, 8 patients with endometriosis and all patients with uterine leiomyomata and from implants from 8 patients with endometriosis. Serum antibody titers in patients with endometriosis or leiomyomata were significantly higher against endometrial or implant antigens from patients with endometriosis and 2 patients with leiomyomata than those against the controls' endometrium. Peritoneal fluid endometrial antibody titers failed to reflect these antigenic differences. Controls and patients with adenomyosis had low titers of endometrial antibodies in their serum or peritoneal fluid. Antigenic differences appear to exist between the endometrium of patients with endometriosis and that of controls.

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Antibodies, Neoplasm Autoantibodies Endometriosis Leiomyoma Uterine Neoplasms Adult Antibodies, Neoplasm Antibodies, Neoplasm Ascitic Fluid Ascitic Fluid Autoantibodies Autoimmunity Autoimmunity Endometriosis Female Hemagglutination Tests Hemagglutination Tests Humans Leiomyoma Uterine Neoplasms

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (23)

Source provenance

europepmc
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