Seminal Plasma Promotes Lesion Development in a Xenograft Model of Endometriosis

Jonathan T McGuane; Katherine M Watson; Jamie Zhang; M Zahied Johan; Zhao Wang; Gabriel Kuo; David J Sharkey; Sarah A Robertson; M Louise Hull

doi:10.1016/j.ajpath.2015.01.010

Seminal Plasma Promotes Lesion Development in a Xenograft Model of Endometriosis

Jonathan T McGuane, Katherine M Watson, Jamie Zhang, M Zahied Johan, Zhao Wang, Gabriel Kuo, David J Sharkey, Sarah A Robertson, M Louise Hull

The American journal of pathology · 2015 · vol. 185(5) , pp. 1409–1422 · doi:10.1016/j.ajpath.2015.01.010 · PMID:25907757 · W2066531745

article OA: bronze CC0 ⤵ 6 in-corpus citations

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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

This study found that seminal plasma enhanced lesion growth and development in a xenograft model of endometriosis.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Endometriosis Endometriosis Semen Adult Animals Disease Models, Animal Endometriosis Endometrium Endometrium Female Heterografts Humans Male Mice Mice, SCID Middle Aged

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (84)

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Altered expression of a cell-cycle suppressor gene, Tob-1, in endometriotic cells by cDNA array analyses via openalex
Altered Transcriptional Regulation of Cytokines, Growth Factors, and Apoptotic Proteins in the Endometrium of Infertile Women with Chronic Endometritis via openalex
Association between endometriosis and cancer: A comprehensive review and a critical analysis of clinical and epidemiological evidence via openalex
Behaviour of Cytokine Levels in Serum and Peritoneal Fluid of Women with Endometriosis via openalex
Coitus during menses. Its effect on endometriosis and pelvic inflammatory disease. via openalex
Decreased concentrations of soluble interleukin-1 receptor accessory protein levels in the peritoneal fluid of women with endometriosis via openalex
Development and prevention of postsurgical adhesions in a chimeric mouse model of experimental endometriosis via openalex
Economic burden of endometriosis via openalex
Effect of human seminal fluid on the growth of endometrial cells of women with endometriosis via openalex
Effect of vascular endothelial growth factor and interleukin-1β on apoptosis in endometrial cell cultures from patients with endometriosis and controls via openalex
Elevated ghrelin levels in the peritoneal fluid of patients with endometriosis: associations with vascular endothelial growth factor (VEGF) and inflammatory cytokines via openalex
Endometrial-Peritoneal Interactions during Endometriotic Lesion Establishment via openalex
Endometriosis, a disease of the macrophage via openalex
Endometriosis is associated with alterations in the relative abundance of proteins and IL-10 in the peritoneal fluid via openalex
Genome-wide association meta-analysis identifies new endometriosis risk loci via openalex
High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysis via openalex
Identification of genes regulated by interleukin-1β in human endometrial stromal cells via openalex
Imbalance in Cytokines from Interleukin‐1 Family – Role in Pathogenesis of Endometriosis via openalex
Increased levels of interleukin-6 and interleukin-10 in the peritoneal fluid of patients with endometriosis via openalex
Induction of an angiogenic phenotype in endometriotic stromal cell cultures by interleukin-1 via openalex
Interleukin-10 attenuates TNF-α–induced interleukin-6 production in endometriotic stromal cells via openalex
Interleukin-1β stimulates the secretion of thymic stromal lymphopoietin (TSLP) from endometrioma stromal cells: possible involvement of TSLP in endometriosis via openalex
Macrophage Activation Factors and Cytokines in Peritoneal Fluid from Patients with Endometriosis via openalex
Macrophages Are Alternatively Activated in Patients with Endometriosis and Required for Growth and Vascularization of Lesions in a Mouse Model of Disease via openalex
Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity via openalex
Profiling of peritoneal fluid of women with endometriosis by chemokine protein array. via openalex
Resveratrol Inhibits Development of Experimental Endometriosis In Vivo and Reduces Endometrial Stromal Cell Invasiveness In Vitro1 via openalex
Role of Endometriosis in Cancer and Tumor Development via openalex
Serum concentrations of growth factors in women with and without endometriosis: the action of anti-endometriosis medicines via openalex
Theories of endometriosis via openalex
The relationship of endometriosis and ovarian malignancy: a review via openalex
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Cited by (6)

Source provenance

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License: CC0 · commercial use OK

[1] A cross-study gene set enrichment analysis identifies critical pathways in endometriosis via openalex

[2] Altered expression of a cell-cycle suppressor gene, Tob-1, in endometriotic cells by cDNA array analyses via openalex

[3] Altered Transcriptional Regulation of Cytokines, Growth Factors, and Apoptotic Proteins in the Endometrium of Infertile Women with Chronic Endometritis via openalex

[4] Association between endometriosis and cancer: A comprehensive review and a critical analysis of clinical and epidemiological evidence via openalex

[5] Behaviour of Cytokine Levels in Serum and Peritoneal Fluid of Women with Endometriosis via openalex

[6] Coitus during menses. Its effect on endometriosis and pelvic inflammatory disease. via openalex

[7] Decreased concentrations of soluble interleukin-1 receptor accessory protein levels in the peritoneal fluid of women with endometriosis via openalex

[8] Development and prevention of postsurgical adhesions in a chimeric mouse model of experimental endometriosis via openalex

[9] Economic burden of endometriosis via openalex

[10] Effect of human seminal fluid on the growth of endometrial cells of women with endometriosis via openalex

[11] Effect of vascular endothelial growth factor and interleukin-1β on apoptosis in endometrial cell cultures from patients with endometriosis and controls via openalex

[12] Elevated ghrelin levels in the peritoneal fluid of patients with endometriosis: associations with vascular endothelial growth factor (VEGF) and inflammatory cytokines via openalex

[13] Endometrial-Peritoneal Interactions during Endometriotic Lesion Establishment via openalex

[14] Endometriosis, a disease of the macrophage via openalex

[15] Endometriosis is associated with alterations in the relative abundance of proteins and IL-10 in the peritoneal fluid via openalex

[16] Genome-wide association meta-analysis identifies new endometriosis risk loci via openalex

[17] High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysis via openalex

[18] Identification of genes regulated by interleukin-1β in human endometrial stromal cells via openalex

[19] Imbalance in Cytokines from Interleukin‐1 Family – Role in Pathogenesis of Endometriosis via openalex

[20] Increased levels of interleukin-6 and interleukin-10 in the peritoneal fluid of patients with endometriosis via openalex

[21] Induction of an angiogenic phenotype in endometriotic stromal cell cultures by interleukin-1 via openalex

[22] Interleukin-10 attenuates TNF-α–induced interleukin-6 production in endometriotic stromal cells via openalex

[23] Interleukin-1β stimulates the secretion of thymic stromal lymphopoietin (TSLP) from endometrioma stromal cells: possible involvement of TSLP in endometriosis via openalex

[24] Macrophage Activation Factors and Cytokines in Peritoneal Fluid from Patients with Endometriosis via openalex

[25] Macrophages Are Alternatively Activated in Patients with Endometriosis and Required for Growth and Vascularization of Lesions in a Mouse Model of Disease via openalex

[26] Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity via openalex

[27] Profiling of peritoneal fluid of women with endometriosis by chemokine protein array. via openalex

[28] Resveratrol Inhibits Development of Experimental Endometriosis In Vivo and Reduces Endometrial Stromal Cell Invasiveness In Vitro1 via openalex

[29] Role of Endometriosis in Cancer and Tumor Development via openalex

[30] Serum concentrations of growth factors in women with and without endometriosis: the action of anti-endometriosis medicines via openalex

[31] Theories of endometriosis via openalex

[32] The relationship of endometriosis and ovarian malignancy: a review via openalex

[33] The Uterine Peristaltic Pump via openalex

[34] The uterine peristaltic pump. Normal and impeded sperm transport within the female genital tract. via openalex

[35] Transforming growth factor-β1 and insulin-like growth factor-1 expression in ovarian endometriotic cysts: a preliminary study via openalex

[36] Uterine peristaltic activity during the menstrual cycle: characterization, regulation, function and dysfunction via openalex

[37] W2145110767 via openalex

[38] W2154685907 via openalex

[39] W2155928769 via openalex

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[60] W2013467558 via openalex

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