Study types
- article 4
- dissertation 1
- other 1
Condition tags
- endometriosis 6
- mesh:D004715 3
- dysmenorrhea 1
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Endometriosis, defined as the growth of endometrial-like tissues outside the uterus, is a common disease among women. Numerous in vivo rodent models of endometriosis have been developed to explore multiple aspects of this poorly understood …
Endometriosis is a gynaecological disease characterised by the growth of endometrial tissues at ectopic sites. Although this disease affects 10-15% of women worldwide, its pathogenesis is still poorly understood. Human eutopic endometrial t…
Transforming growth factor-β1 (TGFB1) is a multifunctional cytokine that is abundant in both endometriotic lesions and the peritoneal fluid in women with endometriosis. However, the role of TGFB1 in the development of endometriosis is as ye…
Endometriosis causes subfertility, pelvic pain and dysmenorrhea, and affects 10% of women of reproductive age globally. The pathology of endometriosis is still poorly understood; however microarray data from a mouse model revealed transform…
TGFβ is likely to significantly influence endometriotic lesion development, as TGFβ KO/SCID mice with no host-derived TGFβ activity have smaller human ectopic endometrial lesions than control mice. TGFβ potentially acts via RUNX2, a transcr…