Carcinosarcoma arising from atypical endometriosis in a cesarean section scar

Leng J, J Leng, Lang J, Jinghe Lang, J Lang, Guo L, L Guo, Lifang Guo, Li H, H Li, Z Liu, Liu Z, Zeyu Liu
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2006 · vol. 16(1) , pp. 432–435 · doi:10.1111/j.1525-1438.2006.00199.x · PMID:16445672 · W2084256187
Review OA: closed CC0 ⤵ 59 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-12 ⓘ

This paper describes a rare case of carcinosarcoma originating from atypical endometriosis within a cesarean section scar.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Malignant change of endometriosis in a cesarean scar (CS) is rare. We report a case of carcinosarcoma arising from atypical endometriosis in a CS scar, which was successfully treated with complete excision of the lesion and repair of the abdominal wall defect with autologous skin-muscle flap graft. A 41-year-old woman presented with a recurrent endometriosis in a CS scar. Within 16 years it changed from benign to atypical endometriosis and finally to carcinosarcoma after three operations. Complete excision of the tumor was performed, with a big defect of abdominal wall successfully repaired by autologous pedicle skin-muscle graft. The diagnosis of carcinosarcoma arising from atypical endometriosis was confirmed histologically. The lesion recurred 6 months after the fourth operation. She died of disease 15 months after the fourth operation. This case demonstrated that long-standing recurrent scar endometriosis could undergo malignant changes and should be made aware. The primary treatment is complete surgical excision.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Carcinosarcoma Cell Transformation, Neoplastic Cesarean Section Cicatrix, Hypertrophic Endometriosis Abdominal Wall Abdominal Wall Adult Adult Biopsy, Needle Biopsy, Needle Carcinosarcoma Carcinosarcoma Carcinosarcoma Cell Transformation, Neoplastic Cell Transformation, Neoplastic Cesarean Section Cesarean Section Cicatrix, Hypertrophic Cicatrix, Hypertrophic

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (9)

Cited by (50)

Source provenance

europepmc
last seen: 2026-10-14T06:08:39.101224+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:03:37.664955+00:00
License: CC0 · commercial use OK