Carcinosarcoma arising from atypical endometriosis in a cesarean section scar

Leng J, J Leng, Lang J, Jinghe Lang, J Lang, Guo L, L Guo, Lifang Guo, Li H, H Li, Z Liu, Liu Z, Zeyu Liu
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2006 · vol. 16(1) , pp. 432–435 · doi:10.1111/j.1525-1438.2006.00199.x · PMID:16445672 · W2084256187
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⚙ AI-generated summary by claude@2026-06, 2026-06-12 ⓘ

This paper describes a rare case of carcinosarcoma originating from atypical endometriosis within a cesarean section scar.

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Abstract

Malignant change of endometriosis in a cesarean scar (CS) is rare. We report a case of carcinosarcoma arising from atypical endometriosis in a CS scar, which was successfully treated with complete excision of the lesion and repair of the abdominal wall defect with autologous skin-muscle flap graft. A 41-year-old woman presented with a recurrent endometriosis in a CS scar. Within 16 years it changed from benign to atypical endometriosis and finally to carcinosarcoma after three operations. Complete excision of the tumor was performed, with a big defect of abdominal wall successfully repaired by autologous pedicle skin-muscle graft. The diagnosis of carcinosarcoma arising from atypical endometriosis was confirmed histologically. The lesion recurred 6 months after the fourth operation. She died of disease 15 months after the fourth operation. This case demonstrated that long-standing recurrent scar endometriosis could undergo malignant changes and should be made aware. The primary treatment is complete surgical excision.

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Condition tags

endometriosis

MeSH descriptors

Carcinosarcoma Cell Transformation, Neoplastic Cesarean Section Cicatrix, Hypertrophic Endometriosis Abdominal Wall Adult Biopsy, Needle Carcinosarcoma Carcinosarcoma Cell Transformation, Neoplastic Cesarean Section Cicatrix, Hypertrophic Cicatrix, Hypertrophic Endometriosis Endometriosis Female Follow-Up Studies Humans Immunohistochemistry

Citation neighborhood

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References (9)

Cited by (50)

Source provenance

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