Intussusception of the appendix: comprehensive review of the literature

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AI-generated summary by claude@2026-07, 2026-07-21

This comprehensive review of 191 appendiceal intussusception cases found it more common in adults, particularly women, with chronic presentations, and frequently associated with endometriosis in adults or inflammation in children.

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Abstract

BackgroundIntussusception of the appendix is a rare disease that constitutes a diagnostic challenge to the surgeon. The literature on this condition is limited to case reports. The demographics, presentation, and treatment remain debatable in the absence of a comprehensive review of the literature.Data sourcesThis article reports a case of a 40-year-old woman who presented with intussusception of the appendix caused by endometriosis. A comprehensive review of the English literature in PubMed was performed. The trends in incidence, sex predilection, presentation, and treatment of appendiceal intussusception were derived based on the reports of 191 patients.CommentsThe incidence was more common in adults (76%) than in children (24%). Female patients (72%) were 2 times more affected in adults than in children, whereas male patients (58%) seem to be more affected in the pediatric population. Intussusception of the appendix has most commonly a chronic presentation (63%). Endometriosis (33%) and inflammation (76%) were the most common pathologic findings in adults and children, respectively. Only 49% of patients were treated by simple appendectomy; 49% patients underwent partial colectomy; and 2% of patients had their appendixes endoscopically removed.

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MeSH descriptors

Appendectomy Appendix Cecal Diseases Ileum Intussusception Adult Anastomosis, Surgical Appendectomy Cecal Diseases Cecal Diseases Cecum Cecum Diagnosis, Differential Female Follow-Up Studies Humans Ileum Intussusception Intussusception Tomography, X-Ray Computed

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europepmc
last seen: 2026-08-01T06:07:04.264727+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:14:11.755070+00:00
License: CC0 · commercial use OK