Appendicular invagination as a rare manifestation of endometriosis

Ana Pardillos Tomé, Pardillos Tomé A, Elena Peña González, Peña González E, Carmelo Cebrián García, Cebrián García C
Revista espanola de enfermedades digestivas · 2020 · vol. 113(1) , pp. 71 · doi:10.17235/reed.2020.7002/2020 · PMID:33054290 · W3091849762
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-10 ⓘ

Endometriosis is an underlying cause of appendicular invagination, a rare condition presenting variably from appendicitis to obstruction, and neoplastic pathology should also be considered.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-10 · read from full text ⓘ

This paper describes appendicular invagination, a rare event (incidence 0.01%), noting that its presentation can mimic acute appendicitis, chronic abdominal pain, intestinal obstruction from intussusception, or be found incidentally on imaging or intraoperatively. It states that endometriosis is the underlying cause of appendicular invagination in one-third of cases, but emphasizes that neoplastic pathology should always be considered when this finding occurs. The main caveat is that the article is a brief letter-type discussion rather than a detailed study with defined methods or patient follow-up. This paper is centrally about endometriosis — specifically endometriosis as a rare cause of appendiceal (appendicular) invagination/intussusception.

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Abstract

Appendicular invagination is a rare situation, with an incidence of 0.01 %. The clinical presentation can be variable from acute appendicitis to chronic abdominal pain, intestinal obstruction by intussusception or simply appear as a radiologic or intraoperative finding. Endometriosis is the underlying cause of appendicular invagination in one-third of cases but the possibility of neoplastic pathology should always be considered in these cases.
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Abstract

Appendicular invagination is a rare situation, with an incidence of 0.01 %. The clinical presentation can be variable from acute appendicitis to chronic abdominal pain, intestinal obstruction by intussusception or simply appear as a radiologic or intraoperative finding. Endometriosis is the underlying cause of appendicular invagination in one-third of cases but the possibility of neoplastic pathology should always be considered in these cases. New comment Comments No comments for this article

References

1. Liang H, Huang M, Wei P, et al. Endometriosis-induced appendiceal intussusceptions. Am J Surg 2009;197:e66–8. 2. Chaar CI, Wexelman B, Zuckerman K, et al. Intussusception of the appendix: comprehensive review of the literature. Am J Surg 2009;198:122–8. 3. Ross WT, Newell JM, Zaino R et al. Appendiceal Endometriosis: is diagnosis dependent on pathology evaluation? A prospective cohort study. J Minim Invasive Gynecol. 2020 Jan 23. pii: S1553-4650(20)30047-9. 4. Cobo C, Marcacuzco A, Manrique A et al. Endometriosis apendicular. Nuestra experiencia en los últimos 11 años. Ginecología y Obstetricia. 2018. Vol.45. Num 2. 5. Guerra Veloz MF, Gómez Rodríguez BJ, Chaaro Benallal D. Endometriosis ileocecal como causa infrecuente de invaginación intestinal. Rev Esp Enferm Dig 2018;110(2):129 Related articles Digestive Diseases Image Cyclic hematochezia in a young woman with appendiceal endometriosis DOI: 10.17235/reed.2022.9257/2022 Letter Surgical indication for right hemicolectomy in goblet cell adenocarcinoma of the appendix DOI: 10.17235/reed.2021.8447/2021 Letter Ileal endometriosis in a patient with Crohn’s disease: a diagnostic challenge DOI: 10.17235/reed.2021.8187/2021 Letter Endometriosis-associated intestinal tumors: a new challenge in clinical practice DOI: 10.17235/reed.2021.8140/2021 Letter Appendiceal goblet-cell adenocarcinoma: a rare cause of acute appendicitis DOI: 10.17235/reed.2021.8056/2021 Letter Laparoscopic management of a small bowel obstruction caused by an endometriotic focus DOI: 10.17235/reed.2019.6220/2019 Letter DOI: 10.17235/reed.2018.5732/2018 Letter to the Editor Bowel obstruction secondary to deep infiltrating endometriosis of the ileum DOI: 10.17235/reed.2018.5364/2017 Letter to the Editor Ileocecal endometriosis as an infrequent cause of intussusception DOI: 10.17235/reed.2017.5183/2017 Digestive Diseases Image Letter to the Editor DOI: 10.17235/reed.2016.4393/2016 Digestive Diseases Image Gastric invagination in adults as a rare cause of constitutional syndrome Letter to the Editor Bowel obstruction secondary to yeyunal intussusception due to gangliocytic paraganglioma DOI: 10.17235/reed.2016.4185/2015 Letter to the Editor Granulomatous appendicitis as an uncommon cause of abdominal pain. Description of a case DOI: 10.17235/reed.2015.3763/2015 Citation tools Pardillos Tomé A, Peña González E, Cebrián García C. Appendicular invagination as a rare manifestation of endometriosis. 7002/2020 Download the citation for this article by clicking on one of the following citation managers: Metrics Publication history Received: 21/02/2020 Accepted: 29/02/2020 Online First: 15/10/2020 Published: 11/01/2021 Article Online First time: 237 days Article editing time: 325 days Share This article has been rated by 1 readers. Reader rating: Valora este artículo: Submit a manuscript Journal info Articles Submit a manuscript Journal info Articles Submit a manuscript The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva Cookie policy Privacy Policy Legal Notice © Copyright 2026 y Creative Commons. The Spanish Journal of Gastroenterology

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Condition tags

endometriosis

MeSH descriptors

Appendicitis Appendix Appendix Appendix Endometriosis Endometriosis Endometriosis Endometriosis Intestinal Obstruction Intestinal Obstruction Intestinal Obstruction Intestinal Obstruction Intussusception Intussusception Intussusception Intussusception Female Humans

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