Minimum Invasive Surgery for Appendiceal Intussusception Caused by Isolated Endometriosis; Surgical Technique for an Unreturned Case

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Laparoscopic partial cecal resection with appendectomy was performed for a case of irreducible appendiceal intussusception caused by endometriosis.

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This case report describes a 47-year-old female with upper abdominal pain and right lower quadrant tenderness, where imaging identified appendiceal intussusception involving the cecum. After failed endoscopic reduction, the patient underwent laparoscopic surgery requiring extracorporeal manipulation due to fixation, resulting in a partial cecal resection and appendectomy because the intussusception was irreparable. Histological analysis confirmed that isolated endometriosis at the appendiceal tip was the underlying cause of this rare Type V intussusception, allowing for a minimally invasive approach despite the complexity. This paper is centrally about endometriosis — specifically illustrating a surgical technique for treating appendiceal involvement caused by deep infiltrating endometriotic lesions.

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Abstract

INTRODUCTION: Appendiceal intussusception is extremely rare, occurring in 0.01% of cases of appendicitis. Endometriosis-related intussusception is the most common in adults. Most reported cases require extensive surgery, such as ileocecal resection or right hemicolectomy. This case presents a minimally invasive surgical approach, involving partial cecal resection for an unreturned case. MATERIALS AND SURGICAL TECHNIQUE: A 47-year-old female presented with upper abdominal pain lasting 2 weeks. Examination revealed tenderness in the right lower quadrant. Imaging confirmed appendiceal intussusception with cecal involvement. Attempts at endoscopic reduction failed, necessitating laparoscopic intervention. The appendix was inaccessible laparoscopically and required extracorporeal manipulation. Due to fixation, intussusception was irreparable. A partial cecal resection with appendectomy was performed. The patient had an uneventful recovery and was discharged on postoperative day two. Histology confirmed endometriosis at the appendiceal tip. DISCUSSION: This case of endometriosis-induced Type V appendiceal intussusception involved complete inversion of the cecum. Unlike most cases that result in extensive resections, our approach demonstrated the feasibility of less invasive surgery. Endometriosis, although an uncommon cause of intussusception, should be considered in differential diagnoses, and CA125 may be a useful diagnostic marker. This case highlights that minimally invasive techniques, including appendectomy with partial cecal resection, should be prioritized in nonreducible cases without malignancy. Individualized, less invasive interventions offer significant benefits for patient recovery and outcomes.
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Abstract

Introduction Appendiceal intussusception is extremely rare, occurring in 0.01% of cases of appendicitis. Endometriosis-related intussusception is the most common in adults. Most reported cases require extensive surgery, such as ileocecal resection or right hemicolectomy. This case presents a minimally invasive surgical approach, involving partial cecal resection for an unreturned case.

Materials

and Surgical Technique A 47-year-old female presented with upper abdominal pain lasting 2 weeks. Examination revealed tenderness in the right lower quadrant. Imaging confirmed appendiceal intussusception with cecal involvement. Attempts at endoscopic reduction failed, necessitating laparoscopic intervention. The appendix was inaccessible laparoscopically and required extracorporeal manipulation. Due to fixation, intussusception was irreparable. A partial cecal resection with appendectomy was performed. The patient had an uneventful recovery and was discharged on postoperative day two. Histology confirmed endometriosis at the appendiceal tip.

Discussion

This case of endometriosis-induced Type V appendiceal intussusception involved complete inversion of the cecum. Unlike most cases that result in extensive resections, our approach demonstrated the feasibility of less invasive surgery. Endometriosis, although an uncommon cause of intussusception, should be considered in differential diagnoses, and CA125 may be a useful diagnostic marker. This case highlights that minimally invasive techniques, including appendectomy with partial cecal resection, should be prioritized in nonreducible cases without malignancy. Individualized, less invasive interventions offer significant benefits for patient recovery and outcomes. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.

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Condition tags

endometriosis

MeSH descriptors

Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (21)

Source provenance

europepmc
last seen: 2026-09-21T06:08:07.822426+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-09-24T06:06:11.764295+00:00
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