New Therapy for Endometriosis
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⤵ 27 in-corpus citations
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This paper describes endometriosis as the growth of endometrial-like tissue outside the uterus, often linked to retrograde menstruation and dependent on estrogen.
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Abstract
Endometriosis is the presence of tissue resembling endometrial glands and stroma outside the uterus. The anatomical sites most often affected by endometriosis are the ovaries, uterosacral ligaments, pelvic peritoneum, rectovaginal septum, cervix, vagina, vulva, and large bowel. Most authorities believe that endometriotic tissue arises as the result of retrograde transport of small fragments of viable endometrium from the uterine cavity through the Fallopian tubes and into the peritoneal cavity. Disease processes such as congenital cervical stenosis, which increase the severity of retrograde menstruation, appear to increase the risk of endometriosis.Endometriotic tissue is completely dependent on estrogen for continued growth. . . .
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References (14)
- Administration of Nasal Nafarelin as Compared with Oral Danazol for Endometriosis via openalex
- Danazol Binding to Rat Androgen, Glucocorticoid, Progesterone, and Estrogen Receptors: Correlation With Biologic Activity via openalex
- Danazol Inhibits Steroidogenesis via openalex
- “MEDICAL OOPHORECTOMY” USING A LONG-ACTING GNRH AGONIST-A POSSIBLE NEW APPROACH TO THE TREATMENT OF ENDOMETRIOSIS. via openalex
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Cited by (27)
- Hsa_circ_0063526 promotes the development of endometriosis by sponging miRNA-141-5p 2021
- Knockdown hsa_circ_0063526 inhibits endometriosis progression via regulating the miR-141-5p / EMT axis and downregulating estrogen receptors 2021
- Gonadotropin-Releasing Hormone and Its Analogues 2020
- Long-term effects on bone mineral density and bone metabolism of 6 months’ treatment with gonadotropin-releasing hormone analogues in Japanese women: comparison of buserelin acetate with leuprolide acetate 2005
- Vesical and vaginal recurrent endometriosis in postmenopause following estrogen replacement therapy 2004
- Gonadotropin Releasing Honnone Agonist and Antagonist for Endometriosis 2003
- Premenstrual and Menstrual Changes in the Macaque and Human Endometrium 2002
- Prospective randomized study comparing the GnRH-agonist leuprorelin acetate and the gestagen lynestrenol in the treatment of severe endometriosis 2001
- Effect of particle size on the prolonged action of subcutaneous danazol in male and female rats 2000
- E- and P-selectin expression in endometriotic tissues and the corresponding endometria 2000
- Expression pattern of integrin adhesion molecules in endometriosis and human endometrium 1998
- Aberrant expression pattern of gap junction connexins in endometriotic tissues 1997
- Uses of GnRH Agonists 1994
- Danazol: Prolonged suppression of gonadotropins after subcutaneous administration in the castrate male rat 1994
- Nafarelin therapy in endometriosis: Long-term effects on bone mineral density 1994
- Endocrine Treatment of Endometriosis 1992
- Time-related effects of gonadotropin-releasing hormone analog treatment in experimentally induced endometriosis in the rat 1991
- Gonadotropin-Releasing Hormone and Its Analogues 1991
- Goserelin 1991
- Endometriosis of Bladder after Menopause 1991
- Treatment of estrogen-dependent gynecological disorders with the gonadotropin releasing hormone agonist buserelin 1991
- GnRH Analogs and Safety 1990
- Nafarelin 1990
- Effects of nafarelin versus danazol on lipids and calcium metabolism 1990
- Transdermal oestrogene application a contraindication in therapy of endometriosis with Gonadotropin-Releasing Hormon analogues 1990
- Pseudotumor Cerebri Induced by Danazol 1989
- A NEW TREATMENT FOR ENDOMETRIOSIS 1989
Source provenance
- europepmc
- last seen: 2026-06-13T06:22:48.782012+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:09:25.758913+00:00
License: CC0
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