Endometriosis in monozygotic twins

Case report OA: closed CC0 ⤵ 92 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

Six of eight monozygotic twin sisters with endometriosis also had the condition, suggesting a strong genetic component for endometriosis.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

OBJECTIVE: To study the reproductive and medical history of monozygotic twin sisters and mothers of patients with endometriosis. MATERIAL AND METHODS: Among 515 patients with endometriosis, eight had a monozygotic twin sister all of whom had had a gynecological laparoscopy or laparotomy. In addition, five of their mothers had had a laparotomy. Details about these 13 relatives were obtained either from medical records (ten cases) or by unmistakable reports from the proband (three cases). RESULT: Six of the monozygotic twin sisters (75%) also had symptomatic endometriosis compared with 3.8% among other types of sisters (p < 0.0005). Three of the mothers (38%) had either endometriosis or adenomyosis. CONCLUSION: This study gives support to the assumption that endometriosis has a genetic trait.

My notes (saved in your browser only)

Condition tags

endometriosisadenomyosis

MeSH descriptors

Diseases in Twins Endometriosis Adult Adult Case-Control Studies Case-Control Studies Cluster Analysis Cluster Analysis Diseases in Twins Diseases in Twins Endometriosis Endometriosis Female Female Humans Humans Laparoscopy Laparoscopy Laparotomy Laparotomy

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (10)

Cited by (50)

Source provenance

europepmc
last seen: 2026-10-17T06:09:56.316927+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:59:25.815134+00:00
unpaywall
last seen: 2026-10-17T06:24:38.187582+00:00
License: CC0 · commercial use OK