Resveratrol impairs cellular mechanisms associated with the pathogenesis of endometriosis

Daniela Madanes; Gabriela Meresman; S Valla; Sofía A Valla; Nourhan Hassan; Ludwig Kiesel; Burkhard Greve; Rosa Inés Barañao; Martin Götte; Analía Gabriela Ricci

doi:10.1016/j.rbmo.2022.02.008

Resveratrol impairs cellular mechanisms associated with the pathogenesis of endometriosis

Daniela Madanes, Gabriela Meresman, S Valla, Sofía A Valla, Nourhan Hassan, Ludwig Kiesel, Burkhard Greve, Rosa Inés Barañao, Martin Götte, Analía Gabriela Ricci

Reproductive biomedicine online · 2022 · vol. 44(6) , pp. 976–990 · doi:10.1016/j.rbmo.2022.02.008 · PMID:35361545 · W4213260915

article OA: green CC0 ⤵ 17 in-corpus citations

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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

Resveratrol was found to inhibit cellular mechanisms crucial to the development and progression of endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometrium Endometrium Endometrium Endometrium Endometrium Female Female Female Female Humans Humans Humans Humans Resveratrol Resveratrol

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References (88)

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Antiangiogenic therapies in endometriosis via openalex
A potential novel treatment strategy: inhibition of angiogenesis and inflammation by resveratrol for regression of endometriosis in an experimental rat model via openalex
Application of the nuclear factor-κB inhibitor BAY 11-7085 for the treatment of endometriosis: an in vitro study via openalex
Characterization of endometrial mesenchymal stem-like cells obtained by endometrial biopsy during routine diagnostics via openalex
Clonogenicity of Human Endometrial Epithelial and Stromal Cells1 via openalex
Collagen I triggers directional migration, invasion and matrix remodeling of stroma cells in a 3D spheroid model of endometriosis via openalex
“Do mad people get endo or does endo make you mad?”: Clinicians’ discursive constructions of Medicine and women with endometriosis via openalex
Effect of Vascular Endothelial Growth Factor Inhibition on Endometrial Implant Development in a Murine Model of Endometriosis via openalex
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Endometriosis and Infertility via openalex
Endometriosis: The Role of Neuroangiogenesis via openalex
Evaluation of apoptosis and angiogenesis in ectopic and eutopic stromal cells of patients with endometriosis compared to non-endometriotic controls via openalex
Expression and Significance of Matrix Metalloproteinase-2 and Matrix Metalloproteinas-9 in Endometriosis via openalex
Expression of MMIF, HIF-1α and VEGF in Serum and Endometrial Tissues of Patients with Endometriosis via openalex
Gene expression profiles and functional characterization of human immortalized endometriotic epithelial and stromal cells via openalex
Identification of an Invasive, N-Cadherin-Expressing Epithelial Cell Type in Endometriosis Using a New Cell Culture Model via openalex
Increased expression of the adult stem cell marker Musashi‐1 in endometriosis and endometrial carcinoma via openalex
Increased telomerase activity and human telomerase reverse transcriptase mRNA expression in the endometrium of patients with endometriosis via openalex
Inhibitory effect of resveratrol on the growth and angiogenesis of human endometrial tissue in an In Vitro three-dimensional model of endometriosis via openalex
Laparoscopic surgery for endometriosis via openalex
Management of Endometriosis: Toward Value-Based, Cost-Effective, Affordable Care via openalex
miR-142-3p Reduces the Size, Migration, and Contractility of Endometrial and Endometriotic Stromal Cells by Targeting Integrin- and Rho GTPase-Related Pathways That Regulate Cytoskeletal Function via openalex
Natural therapies assessment for the treatment of endometriosis via openalex
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Regulation of Matrix Metalloproteinase-2 Activity by COX-2-PGE2-pAKT Axis Promotes Angiogenesis in Endometriosis via openalex
Resveratrol and Endometrium: A Closer Look at an Active Ingredient of Red Wine Using In Vivo and In Vitro Models via openalex
Resveratrol Inhibits Development of Experimental Endometriosis In Vivo and Reduces Endometrial Stromal Cell Invasiveness In Vitro1 via openalex
Resveratrol successfully treats experimental endometriosis through modulation of oxidative stress and lipid peroxidation via openalex
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Stem cells in endometrium and their role in the pathogenesis of endometriosis via openalex
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The Effects of Resveratrol Treatment on Bcl-2 and Bax Gene Expression in Endometriotic Compared with Non-Endometriotic Stromal Cells via openalex
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Cited by (17)

Source provenance

europepmc: last seen: 2026-06-11T06:19:48.454388+00:00
openalex: last seen: 2026-06-10T17:14:06.276822+00:00
pubmed: last seen: 2026-05-27T00:34:54.067244+00:00

License: CC0 · commercial use OK

[1] Angiogenesis lymphangiogenesis and neurogenesis in endometriosis via openalex

[2] Antiangiogenic therapies in endometriosis via openalex

[3] A potential novel treatment strategy: inhibition of angiogenesis and inflammation by resveratrol for regression of endometriosis in an experimental rat model via openalex

[4] Application of the nuclear factor-κB inhibitor BAY 11-7085 for the treatment of endometriosis: an in vitro study via openalex

[5] Characterization of endometrial mesenchymal stem-like cells obtained by endometrial biopsy during routine diagnostics via openalex

[6] Clonogenicity of Human Endometrial Epithelial and Stromal Cells1 via openalex

[7] Collagen I triggers directional migration, invasion and matrix remodeling of stroma cells in a 3D spheroid model of endometriosis via openalex

[8] “Do mad people get endo or does endo make you mad?”: Clinicians’ discursive constructions of Medicine and women with endometriosis via openalex

[9] Effect of Vascular Endothelial Growth Factor Inhibition on Endometrial Implant Development in a Murine Model of Endometriosis via openalex

[10] Endometriosis via openalex

[11] Endometriosis via openalex

[12] Endometriosis and Infertility via openalex

[13] Endometriosis: The Role of Neuroangiogenesis via openalex

[14] Evaluation of apoptosis and angiogenesis in ectopic and eutopic stromal cells of patients with endometriosis compared to non-endometriotic controls via openalex

[15] Expression and Significance of Matrix Metalloproteinase-2 and Matrix Metalloproteinas-9 in Endometriosis via openalex

[16] Expression of MMIF, HIF-1α and VEGF in Serum and Endometrial Tissues of Patients with Endometriosis via openalex

[17] Gene expression profiles and functional characterization of human immortalized endometriotic epithelial and stromal cells via openalex

[18] Identification of an Invasive, N-Cadherin-Expressing Epithelial Cell Type in Endometriosis Using a New Cell Culture Model via openalex

[19] Increased expression of the adult stem cell marker Musashi‐1 in endometriosis and endometrial carcinoma via openalex

[20] Increased telomerase activity and human telomerase reverse transcriptase mRNA expression in the endometrium of patients with endometriosis via openalex

[21] Inhibitory effect of resveratrol on the growth and angiogenesis of human endometrial tissue in an In Vitro three-dimensional model of endometriosis via openalex

[22] Laparoscopic surgery for endometriosis via openalex

[23] Management of Endometriosis: Toward Value-Based, Cost-Effective, Affordable Care via openalex

[24] miR-142-3p Reduces the Size, Migration, and Contractility of Endometrial and Endometriotic Stromal Cells by Targeting Integrin- and Rho GTPase-Related Pathways That Regulate Cytoskeletal Function via openalex

[25] Natural therapies assessment for the treatment of endometriosis via openalex

[26] Pathogenesis of endometriosis: Look no further than John Sampson via openalex

[27] Plant-derived medicines for treatment of endometriosis: A comprehensive review of molecular mechanisms via openalex

[28] Plants as source of new therapies for endometriosis: a review of preclinical and clinical studies via openalex

[29] Regression of Endometrial Implants by Resveratrol in an Experimentally Induced Endometriosis Model in Rats via openalex

[30] Regulation of apoptotic pathways during endometriosis: from the molecular basis to the future perspectives via openalex

[31] Regulation of Matrix Metalloproteinase-2 Activity by COX-2-PGE2-pAKT Axis Promotes Angiogenesis in Endometriosis via openalex

[32] Resveratrol and Endometrium: A Closer Look at an Active Ingredient of Red Wine Using In Vivo and In Vitro Models via openalex

[33] Resveratrol Inhibits Development of Experimental Endometriosis In Vivo and Reduces Endometrial Stromal Cell Invasiveness In Vitro1 via openalex

[34] Resveratrol successfully treats experimental endometriosis through modulation of oxidative stress and lipid peroxidation via openalex

[35] Roles of cell migration and invasion mediated by Twist in endometriosis via openalex

[36] Stem cells in endometrium and their role in the pathogenesis of endometriosis via openalex

[37] Surgical Treatment of Endometriosis via openalex

[38] The Effects of Resveratrol Treatment on Bcl-2 and Bax Gene Expression in Endometriotic Compared with Non-Endometriotic Stromal Cells via openalex

[39] The ellagic acid metabolites urolithin A and B differentially affect growth, adhesion, motility, and invasion of endometriotic cells <i>in vitro</i> via openalex

[40] The modulating effects of Resveratrol on the expression of MMP-2 and MMP-9 in endometriosis women: a randomized exploratory trial via openalex

[41] The Pathogenesis of Endometriosis: Molecular and Cell Biology Insights via openalex

[42] Therapeutic Approaches of Resveratrol on Endometriosis via Anti-Inflammatory and Anti-Angiogenic Pathways via openalex

[43] The Role of Stem Cells in the Etiology and Pathophysiology of Endometriosis via openalex

[44] World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: IV. Tissue collection, processing, and storage in endometriosis research via openalex

[45] γ‐Secretase inhibition affects viability, apoptosis, and the stem cell phenotype of endometriotic cells via openalex

[46] W2557072671 via openalex

[47] W1588588849 via openalex

[48] W1975833165 via openalex

[49] W1984081070 via openalex

[50] W1994719482 via openalex

[51] W2009306864 via openalex

[52] W2012077091 via openalex

[53] W2015376049 via openalex

[54] W2020292262 via openalex

[55] W2027994069 via openalex

[56] W2041683594 via openalex

[57] W2079224311 via openalex

[58] W2082651352 via openalex

[59] W2084251750 via openalex

[60] W2093246348 via openalex

[61] W2104612192 via openalex

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[63] W2136263732 via openalex

[64] W2148737083 via openalex

[65] W2149918525 via openalex

[66] W2175100915 via openalex

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[82] W3011177534 via openalex

[83] W3017571548 via openalex

[84] W3148719272 via openalex

[85] W3158336611 via openalex

[86] W6645389484 via openalex

[87] W6680261372 via openalex

[88] W6782015925 via openalex