Massive peritoneal fluid and markedly elevated serum CA125 and CA19‐9 levels associated with an ovarian endometrioma

Byung-Joon Park, Byung‐Joon Park, Tae-Eung Kim, Tae‐Eung Kim, Yong-Wook Kim, Yong‐Wook Kim
Journal of Obstetrics and Gynaecology Research · 2009 · vol. 35(5) , pp. 935–939 · doi:10.1111/j.1447-0756.2009.01122.x · PMID:20149044 · W2037725505
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This case report describes a 34-year-old woman with massive peritoneal fluid and markedly elevated CA125 and CA19-9 levels due to a ruptured ovarian endometrioma, mimicking malignancy.

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Abstract

Endometriosis associated with ascites is an uncommon condition, but nevertheless important because it mimics the presentation of ovarian malignancy. We present the case of a 34-year-old woman who was admitted with the acute onset of abdominal pain and distension. A pelvic sonogram showed a large amount of peritoneal fluid with echogenic material and a 10-cm complex cystic structure, which appeared to be an enlarged left ovary. The concentrations of CA125 and CA19-9 were 548.1 and 7604 IU/mL, respectively. On the second day of admission, an exploratory laparoscopy was performed, which revealed a ruptured left ovarian cyst consistent with an endometrioma. A laparoscopic left adnexectomy was therefore performed. The histological examination of the specimen confirmed the diagnosis of an endometrioma. After a 12-month follow-up period, the patient showed no recurrence of the endometrioma or peritoneal fluid accumulation. In most instances, the presence of massive ascites is associated with malignancies, tuberculosis, or a perforated viscus. The information provided in the present report is important to both gynecologists and oncologists because it shows that an ovarian cyst with ascites and highly elevated CA125 and CA19-9 levels might be benign.

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Condition tags

mesh:D004715endometriosisendometrioma

MeSH descriptors

Ascites CA-125 Antigen CA-19-9 Antigen Endometriosis Ovarian Diseases Adult Ascites Ascites Ascites Ascitic Fluid Ascitic Fluid CA-125 Antigen CA-19-9 Antigen Diagnosis, Differential Endometriosis Endometriosis Endometriosis Female Humans Ovarian Diseases

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (16)

Cited by (14)

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