Endometriosi: il punto di vista dell’anatomo-patologo. Valutazioni morfologiche ed immunoistochimiche
This paper reviews the morphological and immunohistochemical evaluations of endometriosis, noting its prevalence, histological characteristics, and classification patterns.
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This paper discusses endometriosis from the anatomopathologist’s perspective, focusing on morphological patterns and immunohistochemical evaluation, based on 1,560 histologic cases from 1,114 women (with detailed note of 330 biopsies in 2003) analyzed at Policlinico Gemelli. It describes typical histology as the presence of both epithelial and stromal components, highlights the four-pattern classification proposed by Abrao et al. (differentiated glandular, pure stromal, mixed, and undifferentiated glandular), and notes that some lesions may be difficult to interpret on H&E alone, requiring immunohistochemistry; markers mentioned include cytokeratins 7, CA 125, and CD10. A limitation explicitly acknowledged is that immunohistochemical markers can be nonspecific (e.g., CD10 positivity in certain neoplastic and mesothelial contexts), and morphological atypia/endometriosis-associated malignancy is emphasized as a context requiring careful interpretation. This paper is centrally about endometriosis — it reviews diagnostic morphology and immunohistochemical tools, and relates endometriosis patterns and atypia to treatment response and malignant transformation.
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References (9)
- CD10 and calretinin staining of endocervical glandular lesions, endocervical stroma and endometrioid adenocarcinomas of the uterine corpus: CD10 positivity is characteristic of, but not specific for, mesonephric lesions and is not specific for endometrial stroma via openalex
- CD10 is useful in demonstrating endometrial stroma at ectopic sites and in confirming a diagnosis of endometriosis via openalex
- Comparative immunohistochemical studies of endometriosis lesions and endometriotic cysts via openalex
- Histological classification of endometriosis as a predictor of response to treatment via openalex
- Localization of laminin, fibronectin, E-cadherin, and integrins in endometrium and endometriosis via openalex
- Loss of heterozygosity on 10q23.3 and mutation of the tumor suppressor gene PTEN in benign endometrial cyst of the ovary: possible sequence progression from benign endometrial cyst to endometrioid carcinoma and clear cell carcinoma of the ovary. via openalex
- Morphological and immunohistochemical characterization of an endometriotic cyst of the liver: diagnostic approach to endometriosis via openalex
- Polypoid Endometriosis via openalex
- W2045555409 via openalex
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- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00