Gian Franco Zannoni

ORCID: 0000-0002-4473-7560 · 33 papers in corpus · active 2002-2025

Study types

  • article 18
  • review 6
  • letter 3
  • other 3
  • case-report 2

Condition tags

  • endometriosis 21
  • adenomyosis 8
  • infertility 2
  • bowel_endometriosis 1
  • endometrioma 1
  • disambig:endometritis 1
  • chronic_pelvic_pain 1
article 2025
·doi:10.1158/1538-7445.ovarian25-pr018

Abstract Evidence suggests that certain histotypes of ovarian carcinoma -mainly clear cell (CCOC) and endometrioid (EOC) carcinoma-may arise from endometriosis (EAOC), although the biological mechanisms underlying this phenomenon remain unc…

other 2025
Facts, views & vision in ObGyn ·doi:10.52054/FVVO.2025.183

Hysteroscopic metroplasty improves reproductive outcomes in women with a dysmorphic uterus, but the impact of adenomyosis in these patients is uncertain. We retrospectively analysed 69 women who underwent metroplasty for a dysmorphic uterus…

case-report 2025
Pathologica ·doi:10.32074/1591-951X-1221

The AFF2 gene encodes a protein involved in transcriptional regulation and chromatin remodeling. While primarily associated with Fragile X syndrome, AFF2 fusions have recently been identified in certain malignancies, mostly sinonasal squamo…

article 2024
·doi:10.1158/1538-7445.am2024-3647

Abstract Endometriosis represents a pressing medical concern, imposing a relevant burden on patients including potential malignant transformation into endometriosis-associated ovarian cancer (EAOC). Despite the process of cancer development…

article 2023
·doi:10.1136/ijgc-2023-esgo.35
article 2023
Pathology, research and practice ·doi:10.1016/j.prp.2023.155062

HPV-independent in situ adenocarcinomas have been only recently added to the WHO 2020 classification. To date, little information has been published about HPVindependent precursor lesions. In particular, regardiong the extremely rare cervic…

letter 2023
Virchows Archiv : an international journal of pathology ·doi:10.1007/s00428-023-03659-7
meta-analysis 2023
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society ·doi:10.1136/ijgc-2022-004014

OBJECTIVE: In endometrial carcinoma patients, sentinel lymph node bilateral mapping fails in 20-25% of cases, with several factors affecting the likelihood of detection. However, pooled data about predictive factors of failure are lacking. …

review 2022
Pathobiology : journal of immunopathology, molecular and cellular biology ·doi:10.1159/000521105

Background: A better endometrial cancer (EC) prognosis in patients with coexistent adenomyosis has been hypothesized based on a different prevalence of favorable EC histological prognostic factors. However, pooled risk of EC unfavorable his…

review 2021
Cancers ·doi:10.3390/cancers13194918

A better endometrial cancer (EC) prognosis in patients with coexistent adenomyosis has been reported. Unfortunately, it is still unclear if this better prognosis is related to a more favorable clinical profile of adenomyosis patients. We ai…

review 2021
International Journal of Gynecology & Obstetrics ·doi:10.1002/ijgo.13818

BACKGROUND: Despite the high prevalence of adenomyosis in hysterectomy specimens of endometrial carcinoma (EC) patients, the relationship between adenomyosis and EC prognosis appears unclear. OBJECTIVE: To assess the prognostic value of coe…

article 2021
review 2020
Anticancer research ·doi:10.21873/anticanres.14212

Endometriosis is an estrogen-dependent disease, which affects 10% of women in the reproductive age. Malignant transformation is an uncommon event, which affects approximately 0.7-2.5% of women, and, when it occurs, it involves ovarian and e…

article 2020
Gynecologic and obstetric investigation ·doi:10.1159/000508225

INTRODUCTION: Endometriosis is a common benign gynecological condition that can be associated with a slightly increased risk of developing a wide range of malignancies. CASE PRESENTATION: We herein report a singular case of a 62-year-old wo…

other 2019
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society ·doi:10.1136/ijgc-2018-000045

OBJECTIVES: To describe sonographic features of the microcystic elongated and fragmented (MELF) pattern of myometrial invasion (MI) using the International Endometrial Tumor Analysis (IETA) criteria; to assess the effect of the MELF pattern…

review 2019
Gynecologic and obstetric investigation ·doi:10.1159/000499019

BACKGROUND: We reviewed published cases of uterus-like mass (U-LM), endomyometriosis, polypoid adenomyoma (PA), adenomyomatous polyp, atypical PA (APA), and adenomyoma. SEARCH METHODS: PubMed, Medline, and Scopus searches of all cases publi…

article 2018
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology ·doi:10.1002/uog.19171

OBJECTIVE: To describe the clinical and ultrasound characteristics of ovarian pure clear cell carcinoma. METHODS: This was a retrospective study involving data from 11 ultrasound centers. From the International Ovarian Tumor Analysis (IOTA)…

article 2018
Journal of minimally invasive gynecology ·doi:10.1016/j.jmig.2018.02.023
article 2018
·doi:10.1002/uog.19261

To describe sonographic features of the microcystic elongated and fragmented (MELF) pattern of myometrial invasion (MI) using the International Endometrial Tumor Analysis (IETA) criteria; to assess the effect of the MELF pattern on preopera…

other 2014
Virchows Archiv : an international journal of pathology ·doi:10.1007/s00428-014-1599-1

Ovarian clear cell carcinoma (OCCC) is a subtype of epithelial ovarian cancer with characteristic biological features and aggressive clinical behavior. OCCCs show a pattern of gene mutations different from other type I ovarian malignancies,…

article 2013
·doi:10.5301/je.5000169

Case Report We report a case of bowel endometriosis complicated by spontaneous hemoperitoneum and miscarriage in a 33-year-old primigravida at the 24 th week of gestation. An emergency laparotomy showed spontaneous rupture of the left uteri…

article 2013
La Radiologia medica ·doi:10.1007/s11547-013-0336-1
case-report 2011
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/PGP.0b013e31820dc776
article 2011
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.05.078
article 2010
·doi:10.1093/humrep/de.25.s1.242

Introduction: Endometriosis, defined as the growth of endometrial tissue outside \nthe uterine cavity is a common gynaecological disorder affecting 10-15% \nof women in their reproductive years. It is a major clinical problem causing in- \n…