Endometrioid type adenocarcinoma in situ as a potential precursor lesion for extremely rare invasive endometrioid type adenocarcinoma of the cervix

Gian Franco Zannoni, Zannoni GF, Angela Santoro, Santoro A, Francesca Addante, Addante F, Federica Cianfrini, Cianfrini F, Simona Stolnicu
Pathology, research and practice · 2023 · vol. 254 , pp. 155062 · doi:10.1016/j.prp.2023.155062 · PMID:38199133 · W4390191662
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This paper discusses endometrioid type adenocarcinoma in situ as a potential precursor lesion for an exceptionally rare form of invasive endometrioid type adenocarcinoma originating in the cervix.

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Abstract

HPV-independent in situ adenocarcinomas have been only recently added to the WHO 2020 classification. To date, little information has been published about HPVindependent precursor lesions. In particular, regardiong the extremely rare cervical endometrioid type adenocarcinoma thought to arise in the setting of cervical endometriosis, a premalignant lesion is still not well defined. In this short communication we describe a possible precursor to invasive cervical endometrioid type adenocarcinoma in a 39-yr-old patient, with a previous history of breast cancer.

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MeSH descriptors

Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ Adenocarcinoma in Situ

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