Advances in Endometriosis Research: From Pathogenesis to Prevention

Ashish Ashish, Shivani Mishra, Sangeeta Rai, Kusum Kusum, Gunjan Rai, Royana Singh
In: Obstetrics and Gynecology · 2024 · doi:10.5772/intechopen.1007830 · W4405508631
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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

This chapter analyzes genetic and environmental factors contributing to endometriosis, detailing recent genomic research on susceptibility, progression, and therapeutic targets to inform personalized medicine.

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Abstract

This chapter provides a comprehensive analysis of the genetic factors and environmental influences contributing to endometriosis, highlighting recent advances in genomic research and their implications for personalized medicine approaches. It delves into the genetic underpinnings of endometriosis, exploring the latest research findings on genetic factors that contribute to susceptibility, disease progression, and potential therapeutic targets. The chapter provides insight through a review of Genome-Wide Association Studies (GWAS) and candidate gene studies, highlighting the key genetic variants associated with endometriosis. Additionally, it discusses the complex interplay between genetic predisposition and environmental factors in the development of endometriosis. Furthermore, it explores emerging technologies and methodologies, such as next-generation sequencing (NGS) and functional genomics, for unraveling the genetic complexity of endometriosis. Finally, the chapter discusses the implications of genetic research for personalized diagnosis, treatment, and prevention strategies in endometriosis management. These findings have the potential to significantly impact clinical practice and patient outcomes, paving the way for earlier diagnosis, targeted therapies, and improved quality of life for individuals affected by endometriosis.

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endometriosis

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